Onyx® in endovascular treatment of cerebral arteriovenous malformations : a review

doi:10.12659/PJR.889120

Onyx® in endovascular treatment of cerebral arteriovenous ...

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dc.contributor.author	Szajner, Maciej	pl
dc.contributor.author	Roman, Tomasz	pl
dc.contributor.author	Markowicz, Justyna	pl
dc.contributor.author	Szczerbo-Trojanowska, Małgorzata	pl
dc.date.accessioned	2017-09-05T08:18:39Z
dc.date.available	2017-09-05T08:18:39Z
dc.date.issued	2013	pl
dc.identifier.issn	1733-134X	pl
dc.identifier.uri	http://ruj.uj.edu.pl/xmlui/handle/item/43820
dc.language	eng	pl
dc.rights	Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode	*
dc.title	Onyx® in endovascular treatment of cerebral arteriovenous malformations : a review	pl
dc.type	JournalArticle	pl
dc.description.physical	35-41	pl
dc.description.additional	Bibliogr. s. 40-41	pl
dc.abstract.en	Arteriovenous malformation (AVM) is an abnormal connection between arteries and veins, bypassing the capillary system. In most cases, the disorder may be asymptomatic. The objective of endovascular AVM treatment is set individually for each case upon consultations with a neurosurgeon and a neurologist. The endpoint of the treatment should consist in prevention of AVM bleeding in a management procedure characterized by a significantly lower risk of complications as compared to the natural history of AVM. Endovascular interventions within AVM may include curative exclusion of AVM from circulation, embolization adjuvant to resection or radiation therapy, targeted closure of a previously identified bleeding site as well as palliative embolization. Onyx was first described in the 1990s. It is a non-adhesive and radiolucent compound. Onyx-based closure of the lumen of the targeted vessel is obtained by means of precipitation. The process is enhanced peripherally to the main flux of the injected mixture. This facilitates angiographic monitoring of embolization at any stage. The degree of lumen closure is associated with the location of the vessel. Supratentorial and cortical locations are most advantageous. Dense and plexiform structure of AVM nidus as well as a low number of supplying vessels and a single superficial drainage vein are usually advantageous for Onyx administration. Unfavorable factors include nidus drainage into multiple compartments as well as multiarterial supply of the AVM, particularly from meningeal arteries, en-passant arteries or perforating feeders. Onyx appears to be a safe and efficient material for embolization of cerebral AVMs, also in cases of intracranial bleeding associated with AVM. Curative embolization of small cerebral AVMs is an efficient and safe alternative to neurosurgical and radiosurgical methods. Careful angiographic assessment of individual arteriovenous malformations should be performed before each Onyx administration.	pl
dc.subject.en	Onyx	pl
dc.subject.en	brain arteriovenous malformation	pl
dc.subject.en	embolization	pl
dc.description.volume	78	pl
dc.description.number	3	pl
dc.identifier.doi	10.12659/PJR.889120	pl
dc.identifier.eissn	1899-0967	pl
dc.title.journal	Polish Journal of Radiology	pl
dc.language.container	eng	pl
dc.subtype	ReviewArticle	pl
dc.rights.original	CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0;	pl

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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska

Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska