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Onyx® in endovascular treatment of cerebral arteriovenous malformations : a review

Onyx® in endovascular treatment of cerebral arteriovenous ...

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dc.contributor.author Szajner, Maciej pl
dc.contributor.author Roman, Tomasz pl
dc.contributor.author Markowicz, Justyna pl
dc.contributor.author Szczerbo-Trojanowska, Małgorzata pl
dc.date.accessioned 2017-09-05T08:18:39Z
dc.date.available 2017-09-05T08:18:39Z
dc.date.issued 2013 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/43820
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode *
dc.title Onyx® in endovascular treatment of cerebral arteriovenous malformations : a review pl
dc.type JournalArticle pl
dc.description.physical 35-41 pl
dc.description.additional Bibliogr. s. 40-41 pl
dc.abstract.en Arteriovenous malformation (AVM) is an abnormal connection between arteries and veins, bypassing the capillary system. In most cases, the disorder may be asymptomatic. The objective of endovascular AVM treatment is set individually for each case upon consultations with a neurosurgeon and a neurologist. The endpoint of the treatment should consist in prevention of AVM bleeding in a management procedure characterized by a significantly lower risk of complications as compared to the natural history of AVM. Endovascular interventions within AVM may include curative exclusion of AVM from circulation, embolization adjuvant to resection or radiation therapy, targeted closure of a previously identified bleeding site as well as palliative embolization. Onyx was first described in the 1990s. It is a non-adhesive and radiolucent compound. Onyx-based closure of the lumen of the targeted vessel is obtained by means of precipitation. The process is enhanced peripherally to the main flux of the injected mixture. This facilitates angiographic monitoring of embolization at any stage. The degree of lumen closure is associated with the location of the vessel. Supratentorial and cortical locations are most advantageous. Dense and plexiform structure of AVM nidus as well as a low number of supplying vessels and a single superficial drainage vein are usually advantageous for Onyx administration. Unfavorable factors include nidus drainage into multiple compartments as well as multiarterial supply of the AVM, particularly from meningeal arteries, en-passant arteries or perforating feeders. Onyx appears to be a safe and efficient material for embolization of cerebral AVMs, also in cases of intracranial bleeding associated with AVM. Curative embolization of small cerebral AVMs is an efficient and safe alternative to neurosurgical and radiosurgical methods. Careful angiographic assessment of individual arteriovenous malformations should be performed before each Onyx administration. pl
dc.subject.en Onyx pl
dc.subject.en brain arteriovenous malformation pl
dc.subject.en embolization pl
dc.description.volume 78 pl
dc.description.number 3 pl
dc.identifier.doi 10.12659/PJR.889120 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.subtype ReviewArticle pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0; pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska