Jagiellonian University Repository

Morphometric and volumetric study of caudate and putamen nuclei in normal individuals by MRI : effect of normal aging, gender and hemispheric differences

Morphometric and volumetric study of caudate and ...

Show full item record

dc.contributor.author Abedelahi, Ali pl
dc.contributor.author Hasanzadeh, Hadi pl
dc.contributor.author Hadizadeh, Homaioon pl
dc.contributor.author Joghtaie, Mohammad Taghi pl
dc.date.accessioned 2017-09-05T07:43:27Z
dc.date.available 2017-09-05T07:43:27Z
dc.date.issued 2013 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/43814
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode *
dc.title Morphometric and volumetric study of caudate and putamen nuclei in normal individuals by MRI : effect of normal aging, gender and hemispheric differences pl
dc.type JournalArticle pl
dc.description.physical 7-14 pl
dc.description.additional Bibliogr. s. 14 pl
dc.abstract.en Background: The aim of this study was to determine age, gender, and hemispheric differences in the volume of the human neostriatum (striatum) nucleus in healthy humans. Material/Methods: This study was performed on 120 normal human subjects (60 males, 60 females, right-handed) 15-65 years old, divided into two groups: young (<40 yrs) and old (=≥40 yrs). Sectional brain images were obtained via magnetic resonance imaging (MRI), analyzed and processed using the Image-J software, and the striatum volume was calculated using the Cavalieri's principle, retrospectively. Results: The analyses revealed bilateral age-related shrinkage of the putamen in both genders and the putamen and caudate nucleus were significantly smaller in older than in younger subjects (P-value <0.001). The age-related shrinkage of the caudate and putamen nucleus in men and women was about 5%, 5% and 4%, 4%, respectively, and there were statistically significant volume differences between males and females (P-value <0.05). In both genders, a significant rightward asymmetry was observed in the caudate and putamen nucleus (3.89%, 4.21% in men and 4.51%, 3.32% in women). Conclusions: Bilateral age-related shrinkage and rightward asymmetry of the striate nucleus was found in healthy adults and there were significant volume differences between men and women. Obtained results provide useful baseline data on age and gender-related changes of the volume of the striatum. pl
dc.subject.en striate nucleus pl
dc.subject.en age pl
dc.subject.en gender pl
dc.subject.en MRI pl
dc.subject.en morphometry pl
dc.description.volume 78 pl
dc.description.number 3 pl
dc.identifier.doi 10.12659/PJR.889364 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0; pl


Files in this item

This item appears in the following Collection(s)

Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska