Repozytorium Uniwersytetu Jagiellońskiego

MRI brain findings in ephedrone encephalopathy associated with manganese abuse : single-center perspective

MRI brain findings in ephedrone encephalopathy ...

Metadane (Dublin Core)

dc.contributor.author Poniatowska, Renata pl
dc.contributor.author Lusawa, Małgorzata pl
dc.contributor.author Skierczyńska, Agnieszka pl
dc.contributor.author Makowicz, Grzegorz pl
dc.contributor.author Habrat, Bogusław pl
dc.contributor.author Sienkiewicz-Jarosz, Halina pl
dc.date.accessioned 2017-08-10T07:23:25Z
dc.date.available 2017-08-10T07:23:25Z
dc.date.issued 2014 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/43151
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode *
dc.title MRI brain findings in ephedrone encephalopathy associated with manganese abuse : single-center perspective pl
dc.type JournalArticle pl
dc.description.physical 150-155 pl
dc.description.additional Bibliogr. s. 154-155 pl
dc.abstract.en Background: Manganese (Mn) is a well-known toxic agent causing symptoms of parkinsonism in employees of certain branches of industry. Home production of a psychostimulant ephedrone (methcathinone), involving the use of potassium permanganate, became a new cause of intoxications in Poland. Case Report: This article presents clinical symptoms, initial brain MRI findings and characteristics of changes observed in follow-up examinations in 4 patients with manganese intoxication associated with intravenous administration of ephedrone. All patients in our case series presented symptoms of parkinsonism. T1-WI MRI revealed high intensity signal in globi pallidi in all patients; hyperintense lesions in midbrain were observed in three patients, while lesions located in cerebellar hemispheres and pituitary gland in just one patient. The reduction of signal intensity in the affected brain structures was observed in follow-up studies, with no significant improvement in clinical symptoms. Conclusions: Brain MRI is helpful in the assessment of distribution as well as dynamics of changes in ephedrone encephalopathy. Regression of signal intensity changes visible in brain MRI is not associated with clinical condition improvement. Although brain MRI findings are not characteristic for ephedrone encephalopathy, they may contribute to diagnosing this condition. pl
dc.subject.en brain diseases pl
dc.subject.en metabolic - ultrasonography pl
dc.subject.en manganese compounds pl
dc.description.volume 79 pl
dc.identifier.doi 10.12659/PJR.889690 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0; pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska Poza zaznaczonymi wyjątkami, licencja tej pozycji opisana jest jako Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska