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Contrast-enhanced ultrasonography for the determination of Crohn's disease activity : preliminary experience

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Contrast-enhanced ultrasonography for the determination of Crohn's disease activity : preliminary experience

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dc.contributor.author Białecki, Marcin pl
dc.contributor.author Białecka, Agnieszka pl
dc.contributor.author Laskowska, Katarzyna pl
dc.contributor.author Kłopocka, Maria pl
dc.contributor.author Leibert, Ariel pl
dc.contributor.author Lemanowicz, Adam pl
dc.contributor.author Serafin, Zbigniew pl
dc.date.accessioned 2017-08-09T08:05:06Z
dc.date.available 2017-08-09T08:05:06Z
dc.date.issued 2014 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/43135
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode *
dc.title Contrast-enhanced ultrasonography for the determination of Crohn's disease activity : preliminary experience pl
dc.type JournalArticle pl
dc.description.physical 70-74 pl
dc.description.additional Bibliogr. s. 74 pl
dc.abstract.en Background: Contrast-enhanced ultrasound (CEUS) is a recent non-invasive modality, which may partially replace currently used techniques (endoscopy, CT enterography and MR enterography) in the diagnostics and assessment of Crohn's disease (CD). The aim of the study was to analyze early experience in the use of CEUS for the measurement of activity and staging of CD. Material and Methods: Eleven patients previously diagnosed with CD were included in the study. They underwent contrast-enhanced ultrasonography (SonoVue, Bracco), low-dose CT enterography (LDCTE), assessment of laboratory markers of inflammation and clinical CD activity index (CDAI). Contrast enhancement was evaluated using a semi-quantitative method and a quantitative method that included measurement of peak enhancement (PE), enhancement curve rise time (RT) and wash-in-rate (WiR). Results: Ileal wall thickening was observed in all patients. Semi-quantitative method was used to observe CD activity in CEUS in 10 cases that perfectly matched LDCTE findings. There was a moderate positive correlation between PE and CDAI (r=0.65, p<0.001). There was no significant relationship between perfusion parameters and laboratory markers of inflammation. Conclusions: CEUS is a promising modality for non-invasive assessment of pathologic ileal vascularization in the course of Crohn's disease. Intensity of enhancement in CEUS reflects activity of the disease detected in LDCTE and correlates with CDAI. pl
dc.subject.en Crohn's disease pl
dc.subject.en IBS pl
dc.subject.en CEUS pl
dc.description.volume 79 pl
dc.identifier.doi 10.12659/PJR.890312 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0; pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska