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Polarized xenon for medical applications


Polarized xenon for medical applications

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dc.contributor.advisor Dohnalik, Tomasz [SAP11005099] pl
dc.contributor.author Wojna-Pelczar, Anna [SAP14015403] pl
dc.date.accessioned 2017-08-03T09:40:07Z
dc.date.available 2017-08-03T09:40:07Z
dc.date.submitted 2015-12-11 pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/43080
dc.language eng pl
dc.rights Copyright *
dc.rights.uri http://ruj.uj.edu.pl/4dspace/License/copyright/licencja_copyright.pdf *
dc.title Polarized xenon for medical applications pl
dc.title.alternative Spolaryzowany ksenon do celów medycznych pl
dc.type Thesis pl
dc.place Kraków pl
dc.description.physical 108 pl
dc.abstract.en The hyperpolarized noble gases (xenon 129Xe and helium 3He) delivered a great tool for the growing number of applications, spanning nuclear physics, Medical Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR) spectroscopy studies. Hyperpolarization may be achieved via the Spin Exchange Optical Pumping (SEOP, for 129Xe or 3He) or the Metastability Exchange Optical Pumping (MEOP, 3He). The main aim of this thesis is to present the design of a novel large scale SEOP polarizer, built in the frame of the PhD thesis, for producing hyperpolarized 129Xe for further medical imaging of lungs. Increasing requirements for large volumes of hyperpolarized gases could be realized by e cient polarizers, such as the novel polarizer presented here. The thesis characterizes the optimum operating parameters of the polarizer. The polarizer works basing on the SEOP method, resulting in a high-yield of the polarized gas. The main parts of the unit are presented: the coil system producing magnetic eld, the gas (129Xe and bu er gases: N2, 4He) and rubidium distribution system, the high-power laser diode system spectrally narrowed with Volume Bragg Gratings for rubidium optical pumpin and the high-volume SEOP cell. The SEOP polarizer was designed to work at the pressure close to the atmospheric pressure with a low content of the 129Xe gas in the SEOP mixture, contained in a large SEOP cell (about 6 L inner volume). This is unique comparing to majority of other SEOP designs, which use the high-pressure and small-volume cells. The motivation, a brief overview of the state of the art in the hyper-polarized gases techniques, the current status of the SEOP polarizer project and the future research plans are also part of this work. pl
dc.subject.pl hiperpolaryzacja pl
dc.subject.pl polaryzator pl
dc.subject.pl ksenon-129 pl
dc.subject.pl pompowanie optyczne z wymianą spinu pl
dc.subject.pl MRJ pl
dc.subject.pl laser pl
dc.subject.en nuclear polarization pl
dc.subject.en polarizer pl
dc.subject.en xenon-129 pl
dc.subject.en hyperpolarization pl
dc.subject.en spin exchange optical pumping pl
dc.subject.en MRI pl
dc.subject.en laser pl
dc.identifier.callnumber Dokt. 2015/275 pl
dc.contributor.institution Jagiellonian University. Faculty of Physics, Astronomy and Applied Computer Science. M. Smoluchowski Institute of Physics pl
dc.contributor.reviewer Lisak, Daniel pl
dc.contributor.reviewer Tomanek, Bogusław pl
dc.affiliation Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiego pl
dc.rights.original OTHER; otwarte repozytorium; ostateczna wersja autorska (postprint); w momencie opublikowania; 0; pl
dc.identifier.project POIG.02.02.00-00-003/08 pl
dc.identifier.project DCS/000686/2012 and DCS2014 pl

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