Hippocampal changes in Febrile infection-related epilepsy syndrome (FIRES)

doi:10.12659/PJR.894645

Hippocampal changes in Febrile infection-related epilepsy syndrome (FIRES)

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Hippocampal changes in Febrile infection-related epilepsy syndrome (FIRES)

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title:	Hippocampal changes in Febrile infection-related epilepsy syndrome (FIRES)
author:	Agarwal Amit, Sabat Shyamsunder, Thamburaj Krishnamurthy, Kanekar Sangam
journal title:	Polish Journal of Radiology
volume:	80
date of publication :	2015
pages:	391-394
ISSN:	1733-134X
eISSN:	1899-0967
DOI:	10.12659/PJR.894645
notes:	Bibliogr. s. 393-394
language:	English
journal language:	English
abstract in English:	BACKGROUND: Febrile seizures are the most common seizure disorder in childhood, associated with a significant rise in body temperature. However, post-infectious refractory afebrile form of seizures in previously healthy children is being increasingly recognized in around the world, which evolves into a chronic refractory form of epilepsy. The term 'Febrile infection-related epilepsy syndrome' (FIRES) has been proposed for these conditions and represents a refractory severe post-infectious epileptic condition in previously normal children. CASE REPORT: We report the initial and follow-up MR imaging findings in a 5year-old with refractory epilepsy post-febrile seizures. CONCLUSIONS: In summary, acute post-infectious seizures are increasingly being recognized across the globe with the newly coined term 'Febrile infection-related epilepsy syndrome' (FIRES) for this group of immune-mediated epileptic encephalopathy in previously healthy children. This has three phases: episode of simple febrile infection, followed by acute refractory seizures and lastly the chronic phase of neuropsychological impairments and seizures.
keywords in English:	hippocampus, magnetic resonance imaging, seizures
type:	journal article
subtype:	academic paper

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