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S100B protein, astrocytes and memory

S100B protein, astrocytes and memory

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dc.contributor.author Kiełbiński, Michał [SAP12020127] pl
dc.contributor.author Sołtys, Zbigniew [SAP11012054] pl
dc.date.accessioned 2016-09-27T13:28:39Z
dc.date.available 2016-09-27T13:28:39Z
dc.date.issued 2009 pl
dc.identifier.issn 0324-833X pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/30851
dc.language eng pl
dc.rights Dodaję tylko opis bibliograficzny *
dc.rights.uri *
dc.title S100B protein, astrocytes and memory pl
dc.type JournalArticle pl
dc.description.physical 1-11 pl
dc.abstract.en S100 is a vertebrate-specific family of small, calcium-binding proteins. One of them is the S100B protein, mostly expressed in, and released by astroglial cells in the brain. The protein has been implicated in the regulation of numerous processes including phosphorylation of cytoskeletal proteins, cell proliferation and differentiation, as well as many other functions. This article focuses on the role of S100B in processes relating to learning and memory. More than four decades of behavioral and neurophysiological research have revealed beneficial effects of this protein. However, there is also evidence suggesting that overexpression of S100B can lead to memory dysfunction. It is possible that an increased S100B release from astrocytes may be co-responsible for memory dysfunction observed in the early stages of Alzheimer's disease. pl
dc.subject.en S100B protein pl
dc.subject.en cytoskeleton pl
dc.subject.en memory pl
dc.subject.en astrocytes pl
dc.description.volume 1 pl
dc.description.number 1 pl
dc.identifier.doi 10.2478/v100052-008-0005 pl
dc.identifier.eissn 2080-2218 pl
dc.title.journal Advances in Cell Biology pl
dc.language.container eng pl
dc.affiliation Wydział Biologii i Nauk o Ziemi : Instytut Zoologii pl
dc.subtype Article pl

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