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Formation of poly-L-lysine monolayers on silica : modeling and experimental studies

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Formation of poly-L-lysine monolayers on silica : modeling and experimental studies

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dc.contributor.author Kosior, Dominik pl
dc.contributor.author Morga, Maria pl
dc.contributor.author Maroni, Plinio pl
dc.contributor.author Cieśla, Michał [SAP11018214] pl
dc.contributor.author Adamczyk, Zbigniew pl
dc.date.accessioned 2021-01-08T22:55:50Z
dc.date.available 2021-01-08T22:55:50Z
dc.date.issued 2020 pl
dc.identifier.issn 1932-7447 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/260073
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by/4.0/legalcode.pl *
dc.title Formation of poly-L-lysine monolayers on silica : modeling and experimental studies pl
dc.type JournalArticle pl
dc.description.physical 4571-4581 pl
dc.abstract.en Modification of solid substrates by poly-l-lysine (PLL) layers has been widely employed in order to improve their biocompatibility, for promoting protein and cell immobilization for fabrication of biosensor arrays and antibacterial coatings. However, despite many studies conducted in the literature, there is a deficiency in a quantitative description of PLL adsorption processes. It is postulated that this becomes feasible by applying direct experimental techniques combined with thorough theoretical modeling. In this work, the kinetics of PLL adsorption on silica for various ionic strengths was determined in situ under controlled flow conditions using the optical reflectometry and the streaming potential methods. Both the initial adsorption rates and longer time kinetic runs were acquired and quantitatively interpreted in terms of the convective diffusion and the random sequential adsorption theoretical modeling based on the coarse-grained Monte Carlo approach. This unique combination of experimental and theoretical approaches enabled us to gain new insight into the mechanism of macroion adsorption controlled by the electrostatic interactions, which affect both the molecule conformations and the blocking effects. Besides significance for basic science, the results obtained in this work can be exploited for developing reliable procedures for preparing stable PLL monolayers of well-controlled coverage and electrokinetic properties. pl
dc.description.volume 124 pl
dc.description.number 8 pl
dc.identifier.doi 10.1021/acs.jpcc.9b10870 pl
dc.identifier.eissn 1932-7455 pl
dc.title.journal The Journal of Physical Chemistry. C pl
dc.language.container eng pl
dc.affiliation Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki Teoretycznej pl
dc.subtype Article pl
dc.rights.original CC-BY; inne; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
.pointsMNiSW [2020 A]: 140


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Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa