Polymeric/silicagel hybrid molecularly photoimprinted adsorbents for adenosine and its derivatives

doi:10.1016/j.eurpolymj.2014.07.029

Polymeric/silicagel hybrid molecularly photoimprinted ...

Bibliographic description

punktacja MNiSW [2014 A]: 35

title:	Polymeric/silicagel hybrid molecularly photoimprinted adsorbents for adenosine and its derivatives
author:	Mikulska Anna, Inoue Masamichi, Kuroda Keita, Gut Agnieszka , Yusa Shin-Ichi, Nowakowska Maria , Szczubiałka Krzysztof
Journal title:	European Polymer Journal
volume:	59
date of publication:	2014
pages:	230-238
ISSN:	0014-3057
eISSN:	1873-1945
DOI:	10.1016/j.eurpolymj.2014.07.029
notes:	Na publikacji autorka Gut Agnieszka podpisana jako Iwanowska Agnieszka.
language:	English
Journal language:	English
abstract in english:	The adsorbents of adenosine, a potential cancer biomarker present in physiological fluids, urine in particular, were obtained and studied. The adsorbents were fabricated by coating submicron-sized silica gel particles with ultrathin layers of polymers containing thymine moieties. The thymine groups selectively adsorbed compounds containing adenine, a nucleobase complementary to thymine, via the formation of hydrogen bonds. Irradiation of the adsorbents with light selectively absorbed by thymine chromophores in the presence of adenine as a template molecule resulted in the photochemical molecular imprinting of adenine. The non-imprinted adsorbent showed preferential adenosine adsorption from a solution containing a mixture of nucleosides. The adenine-imprinted materials showed considerably higher than non-imprinted adsorbents selectivity of adenosine adsorption versus other nucleosides.
keywords in english:	adeninea, adenosine, adsorbent, molecular imprinting, photodimerization, thymine
affiliation:	Wydział Chemii : Zakład Chemii Fizycznej i Elektrochemii
type:	journal article
subtype:	academic paper