Mutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexual

2012
journal article
article
5
cris.lastimport.scopus2024-04-24T02:58:12Z
cris.lastimport.wos2024-04-09T20:25:05Z
dc.abstract.enIn a previous theoretical study we investigated whether adaptive or non-adaptive processes are more important in the evolution of senescence. We built a model that combined both processes and found that mutation accumulation is important only at those ages where mortality has a negligible impact on fitness. This model, however, was limited to haploid organisms. Here we extend our model by introducing diploidy and sexual reproduction. We assume that only recessive (mutated) homozygotes experience detrimental effects. Our results corroborate our previous conclusions, confirming that life histories are largely determined by adaptive processes. We also found that the equilibrium frequencies of mutated alleles are at higher values than in haploid model, because mutations in heterozygotes are hidden for directional selection. Nevertheless, the equilibrium frequencies of recessive homozygotes that make mutations visible to selection are very similar to the equilibrium frequencies of these alleles in our haploid model. Diploidy and sexual reproduction with recombination slows down approaching selection-mutation balance.pl
dc.affiliationWydział Biologii i Nauk o Ziemi : Instytut Nauk o Środowiskupl
dc.contributor.authorDańko, Maciej - 143684 pl
dc.contributor.authorKozłowski, Jan - 129382 pl
dc.date.accessioned2016-05-05T11:58:40Z
dc.date.available2016-05-05T11:58:40Z
dc.date.issued2012pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number10pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume7pl
dc.identifier.articleide48302pl
dc.identifier.doi10.1371/journal.pone.0048302pl
dc.identifier.eissn1932-6203pl
dc.identifier.projectROD UJ / Ppl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/24999
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subtypeArticlepl
dc.titleMutation accumulation may only be a minor force in shaping life-history traits, even when reproduction is sexualpl
dc.title.journalPLoS ONEpl
dc.typeJournalArticlepl
dspace.entity.typePublication
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