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Microbiological investigations of oxygen plasma treated parylene C surfaces for metal implant coating

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Microbiological investigations of oxygen plasma treated parylene C surfaces for metal implant coating

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dc.contributor.author Gołda-Cępa, Monika [SAP14010906] pl
dc.contributor.author Brzychczy-Włoch, Monika [SAP20002305] pl
dc.contributor.author Engvall, Klas pl
dc.contributor.author Aminlashgari, Nina pl
dc.contributor.author Hakkarainen, Minna pl
dc.contributor.author Kotarba, Andrzej [SAP11013502] pl
dc.date.accessioned 2015-12-10T10:01:14Z
dc.date.available 2015-12-10T10:01:14Z
dc.date.issued 2015 pl
dc.identifier.issn 0928-4931 pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/18005
dc.language eng pl
dc.title Microbiological investigations of oxygen plasma treated parylene C surfaces for metal implant coating pl
dc.type JournalArticle pl
dc.description.physical 273-281 pl
dc.abstract.en Parylene C surface was modified by the use of oxygen plasma treatment and characterized by microscopic and surface-sensitive techniques (E-SEM, AFM, XPS, LDI–TOF-MS, contact angle). The influence of the treatment on surface properties was investigated by calculations of surface free energy (Owens–Wendt method). Moreover, early adhesion (Culture Plate Method, Optical Microscopy Test) and biofilm formation ability (Cristal Violet Assay) on the parylene C surface was investigated. The bacteria strains which are common causative agents of medical device-associated infections (Staphylococcus aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa — reference strains and clinical isolates) were used. It was concluded that chemical (oxygen insertion) and physical (nanotopography generation) changes, have a significant impact on the biocompatibility in terms of increased hydrophilicity (θw of unmodified sample = 88° ± 2°, θw of 60 min modified sample = 17.6° ± 0.8°) and surface free energy (SFE of unmodified sample = 42.4 mJ/m2, and for 60 min modified sample = 70.1 mJ/m2). At the same time, no statistical effect on biofilm production and bacteria attachment to the modified surface of any of the tested strains was observed. pl
dc.subject.en parylene C pl
dc.subject.en implant coating pl
dc.subject.en oxygen plasma pl
dc.subject.en microbiological evaluation pl
dc.description.volume 52 pl
dc.identifier.doi 10.1016/j.msec.2015.03.060 pl
dc.identifier.eissn 1873-0191 pl
dc.title.journal Materials Science & Engineering. C pl
dc.language.container eng pl
dc.affiliation Wydział Chemii : Zakład Chemii Nieorganicznej pl
dc.affiliation Wydział Lekarski : Zakład Bakteriologii,Ekologii Drobnoustrojów i Parazytologii pl
dc.subtype Article pl
dc.rights.original bez licencji pl
dc.cm.id 73175
.pointsMNiSW [2015 A]: 25


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