Provocation tests with aspirin reliably prove aspirin hypersensitivity in patients with a history of prior reaction to
non-steroidal anti-inflammatory drugs. The nasal provocation test with lysine-aspirin was introduced into clinical
practice in the late 1980s. It is a valuable screening test in patients with aspirin hypersensitivity restricted to the
upper airway and in those with severe asthma in whom oral and bronchial aspirin challenges are contraindicated.
Nasal challenge with lysine-aspirin is relatively simple, cheap and quite easy to be supervised in a hospital outpatient clinic. A positive nasal reaction is defined as the appearance of clinical symptoms such as rhinorrhoea, sneezing and nasal congestion combined with significant decreases in some parameters of rhinomanometry, acoustic
rhinometry and/or peak inspiratory flows. However, a negative nasal challenge should be followed by the oral aspirin test. The detailed protocol of the nasal provocation test with lysine-aspirin is presented in this article.
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nadwrażliwość na kwas acetylosalicylowy
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donosowy test prowokacyjny
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aspiryna lizynowa
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dc.subject.en
aspirin hypersensitivity
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dc.subject.en
nasal provocation test
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dc.subject.en
lysine-aspirin
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dc.description.volume
27
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dc.description.number
3
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dc.identifier.eissn
2299-0046
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dc.title.journal
Postępy Dermatologii i Alergologii
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dc.language.container
pol
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dc.date.accession
2020-06-04
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dc.affiliation
Wydział Lekarski : Klinika Alergii i Immunologii
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dc.affiliation
Wydział Lekarski : Klinika Pulmonologii
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dc.subtype
Article
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dc.rights.original
CC-BY-NC-SA; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa