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Na publikacji autorka Kyzioł Agnieszka podpisana jako Jańczyk Agnieszka.
language:
English
journal language:
English
abstract in English:
The visible light-induced phototoxicity of titanium dioxide modified with platinum(IV) chloride complexes, $[TiO_{2}/PtCl_{4}]$, was tested. In vitro experiments with the mouse melanoma cells (S-91) have demonstrated phototoxicity of the $[TiO_{2}/PtCl_{4}]$ material. Detection of efficiently generated various reactive oxygen species $(\cdot OH, O_{2}\cdot-, H_{2}O_{2}, ^{1}\textrm{O}_{2})$ and also reactive chlorine species has proven the photodynamic activity of the tested material, induced by visible light (
$\lambda$ > 455 nm). The cellular death (recognized as a necrosis) is a result of the cell membrane peroxidation.