Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides

doi:10.5562/cca2106

Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides

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Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides

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dc.contributor.author	Miljanić, Snežana	pl
dc.contributor.author	Dijanošić, Adriana	pl
dc.contributor.author	Kalac, Matea	pl
dc.contributor.author	Radić Stojković, Marijana	pl
dc.contributor.author	Piantanida, Ivo	pl
dc.contributor.author	Pawlica, Dariusz	pl
dc.contributor.author	Eilmes, Julita [SAP11006581]	pl
dc.date.accessioned	2015-09-15T07:55:44Z
dc.date.available	2015-09-15T07:55:44Z
dc.date.issued	2012	pl
dc.identifier.issn	0011-1643	pl
dc.identifier.uri	http://ruj.uj.edu.pl/xmlui/handle/item/15646
dc.language	eng	pl
dc.rights	Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa	*
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/pl/legalcode	*
dc.title	Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides	pl
dc.type	JournalArticle	pl
dc.description.physical	577-584	pl
dc.description.additional	Dariusz Pawlica - Instytut Chemii.	pl
dc.identifier.weblink	https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=139013	pl
dc.abstract.en	Binding modes of a dibenzotetraaza[14]annulene (DBTAA) derivative with synthetic nucleic acids were studied using surface-enhanced Raman spectroscopy (SERS). Changes in SERS intensity and appearance of new bands in spectra were attributed to different complexes formed between the DBTAA molecules and DNA/RNA polynucleotides. A decrease in intensity pointed to intercalation as the dominant binding mode of the annulene derivative with poly dGdC-poly dGdC and poly rA-poly rU, whereas new bands in the spectra at 735 cm−1 and 1345 cm−1 revealed binding within the minor groove of poly dAdT-poly dAdT. When all the dominant binding sites were occupied, SERS spectra implied that small molecules bind on the outside of the DNA analogues, while exist mainly as free molecules in equimolar ratio with the synthetic RNA polynucleotide, thereby indicating higher affinity for DNA than for RNA.	pl
dc.subject.en	surface-enhanced Raman scattering	pl
dc.subject.en	polynucleotide	pl
dc.subject.en	binding	pl
dc.subject.en	annulene	pl
dc.description.volume	85	pl
dc.description.number	4	pl
dc.identifier.doi	10.5562/cca2106	pl
dc.identifier.eissn	1334-417X	pl
dc.title.journal	Croatica Chemica Acta	pl
dc.language.container	eng	pl
dc.date.accession	2019-01-22	pl
dc.affiliation	Wydział Chemii : Zakład Chemii Organicznej	pl
dc.subtype	Article	pl
dc.rights.original	CC-BY; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0	pl
dc.identifier.project	ROD UJ / P	pl
.pointsMNiSW	[2012 A]: 25