Jagiellonian University Repository

Biomicroconcretes based on the hybrid HAp/CTS granules, α-TCP and pectins as a novel injectable bone substitutes

pcg.skipToMenu

Biomicroconcretes based on the hybrid HAp/CTS granules, α-TCP and pectins as a novel injectable bone substitutes

Show full item record

dc.contributor.author Dziadek, Michał [SAP14040948] pl
dc.contributor.author Zima, Aneta pl
dc.contributor.author Cichoń, Ewelina pl
dc.contributor.author Czechowska, Joanna pl
dc.contributor.author Ślósarczyk, Anna pl
dc.date.accessioned 2020-04-28T09:34:03Z
dc.date.available 2020-04-28T09:34:03Z
dc.date.issued 2020 pl
dc.identifier.issn 0167-577X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/154745
dc.language eng pl
dc.rights Dodaję tylko opis bibliograficzny *
dc.rights.uri *
dc.title Biomicroconcretes based on the hybrid HAp/CTS granules, α-TCP and pectins as a novel injectable bone substitutes pl
dc.type JournalArticle pl
dc.abstract.en In this work, novel bone substitutes in the form of biomicroconcretes with high surgical handiness and satisfactory mechanical properties were developed. Materials were composed of hybrid hydroxyapatite/chitosan (HAp/CTS) granules as aggregate, α-TCP as a setting phase, and pectin solutions as a liquid phase. Two types of low esterified amidated pectins from citrus peels (CP) and apple pomace (AP) and also two fractions of HAp/CTS granules of size between 300 and 400 µm and 400–600 µm were used. The presence of pectins significantly improved surgical handiness and allowed to obtain injectable biomicroconcretes. Synergistic effect of fast internal crosslinking of low esterified pectins, induced by Ca2+ released from α-TCP, together with setting reaction of highly reactive α-TCP (dual setting system) resulted in excellent cohesion of the final materials. By the use of different type of pectins (AP, CP) one can control mechanical properties of the materials. The results showed that pectins from citrus peels more effectively improved compressive strength. The biomicroconcretes obtained in this work showed great potential for the use as novel bone substitutes, however, they require further studies, especially biological evaluation. pl
dc.subject.en Biomicroconcretes pl
dc.subject.en Hybrid HAp/CTS granules pl
dc.subject.en Pectins pl
dc.description.volume 265 pl
dc.description.publication 0,6 pl
dc.identifier.doi 10.1016/j.matlet.2020.127457 pl
dc.identifier.eissn 1873-4979 pl
dc.title.journal Materials Letters pl
dc.language.container eng pl
dc.affiliation Wydział Chemii : Zakład Chemii Nieorganicznej pl
dc.subtype Article pl
dc.identifier.articleid 127457 pl
dc.rights.original bez licencji pl
dc.identifier.project ROD UJ / O pl
.pointsMNiSW [2020 A]: 70


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)