Somatic comorbidity in Polish patients with epilepsy

doi:10.20452/pamw.14794

Somatic comorbidity in Polish patients with epilepsy

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Somatic comorbidity in Polish patients with epilepsy

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punktacja MNiSW [2019]: 100

title:	Somatic comorbidity in Polish patients with epilepsy
author:	Bosak Magdalena , Kowalik Monika, Mołek Patrycja, Słowik Agnieszka
journal title:	Polskie Archiwum Medycyny Wewnętrznej = Polish Archives of Internal Medicine
volume:	129
issue:	5
date of publication :	2019
pages:	303-307
ISSN:	0032-3772
eISSN:	1897-9483
DOI:	10.20452/pamw.14794
language:	English
journal language:	English
abstract in English:	A wide spectrum of somatic and psychiatric disorders occurs frequently in patients with epilepsy, which adds to the burden of this disease. The aim of the study was to estimate the prevalence and risk factors of somatic comorbidities and analyze somatic comedication in adult patients with epilepsy. This study involved patients with epilepsy treated in university epilepsy clinic. Data on epilepsy, antiepileptic drugs (AEDs), somatic comorbidities, and their treatment were collected from a structured interview and from medical records. The sample population consisted of 636 patients (mean age, 35.3 years); 380 (59.7%) were female and 241 (37.9%) had well‑controlled epilepsy. At least 1 comorbid somatic condition was found in 216 patients (34%). The most prevalent somatic comorbidities were cardiovascular diseases, allergies, migraine, hyperlipidemia, thyroid disorders, and chronic lower respiratory diseases. Furthermore, 200 patients (31.4%) were prescribed at least 1 medication for somatic disorders. Logistic regression analysis revealed several independent risk factors for the occurrence of somatic comorbidities: older age, shorter duration of epilepsy, lower seizure frequency, and lower number of AEDs. Somatic comorbidities and comedication with non‑AEDs were found in one‑third of the relatively young cohort of adult patients with epilepsy. Patients with pharmacoresistant epilepsy may be at risk of underdiagnosis and undertreatment of somatic comorbidities. The presence of comorbidities may have implications for the diagnosis and treatment of seizure disorder and coexisting condition.
keywords in English:	comedication, epilepsy, somatic comorbidity
departmental parameterization:	100
affiliation:	Wydział Lekarski : Klinika Neurologii, Wydział Lekarski : Zakład Neurogenetyki
type:	journal article
subtype:	academic paper

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