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Preoperative thrombocytosis in surgically treated patients with non-small cell lung cancer

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Preoperative thrombocytosis in surgically treated patients with non-small cell lung cancer

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dc.contributor.author Skorek, Paweł pl
dc.contributor.author Stępień, Konrad pl
dc.contributor.author Fila, Marcin pl
dc.contributor.author Hauer, Jolanta pl
dc.contributor.author Kużdżał, Jarosław [SAP20011888] pl
dc.date.accessioned 2020-01-17T10:00:02Z
dc.date.available 2020-01-17T10:00:02Z
dc.date.issued 2018 pl
dc.identifier.issn 0032-3772 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/143627
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/pl/legalcode *
dc.title Preoperative thrombocytosis in surgically treated patients with non-small cell lung cancer pl
dc.type JournalArticle pl
dc.description.physical 512-517 pl
dc.abstract.en Lung cancer is the most common cause of cancer‑related death. Accurate and easy‑to‑use prognostic factors are necessary. Increased platelet count might be a potential prognostic factor. We aimed to investigate the relationship between thrombocytosis and stage of lung cancer and to assess the frequency and clinical importance of thrombocytosis in this patient group. We retrospectively analyzed hospital records of consecutive patients with non-small cell lung cancer (NSCLC) who underwent curative‑intent pulmonary resections. Of 323 patients, 285 patients with NSCLC were selected (mean [SD] age, 66.55 [8.52] years; men, 63.86%). Squamous cell carcinoma was diagnosed in 130 patients (45.61%); adenocarcinoma, in 128 (44.91%); large cell carcinoma, in 16 (5.61%); and adenosquamous carcinoma, in 11 (3.86%). The prevalence of preoperative thrombocytosis in the whole sample was 10.18% (n = 29). Anemia was more common in patients with thrombocytosis compared with those without thrombocytosis (65.52% vs 30.08%; P <0.001). Thrombocytosis was found in 22.41% of patients with stage III+IV cancer and in 3.82% of those with stage I (P <0.001). Moreover, in patients with no metastases (N0, M0 according to the 7th edition of the TNM classification), thrombocytosis was more frequent in the group with stage II than in that with stage I cancer (3.85% vs 20.00%; P = 0.002). Thrombocytosis was also more frequent in patients with N2 than with N1 disease (9.76% vs 23.81%; P = 0.09). Thrombocytosis is often observed in patients with NSCLC and is significantly associated with the higher stage of disease. pl
dc.subject.en lung cancer pl
dc.subject.en non-small cell lung cancer pl
dc.subject.en paraneoplastic syndrome pl
dc.subject.en prognostic factors pl
dc.subject.en thrombocytosis pl
dc.description.volume 128 pl
dc.description.number 9 pl
dc.description.points 30 pl
dc.identifier.doi 10.20452/pamw.4299 pl
dc.identifier.eissn 1897-9483 pl
dc.title.journal Polskie Archiwum Medycyny Wewnętrznej = Polish Archives of Internal Medicine pl
dc.language.container eng pl
dc.affiliation Wydział Nauk o Zdrowiu : Instytut Fizjoterapii pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-SA; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
dc.cm.id 90251
dc.cm.date 2020-01-07
.pointsMNiSW [2018 A]: 30


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa