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Preoperative thrombocytosis in surgically treated patients with non-small cell lung cancer
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
Preoperative thrombocytosis in surgically treated patients with non-small cell lung cancer
Bibliographic description
| title: | Preoperative thrombocytosis in surgically treated patients with non-small cell lung cancer |
| author: | Skorek Paweł, Stępień Konrad, Fila Marcin, Hauer Jolanta, Kużdżał Jarosław 
|
| journal title: | Polskie Archiwum Medycyny Wewnętrznej = Polish Archives of Internal Medicine |
| volume: | 128 |
| issue: | 9 |
| date of publication : | 2018 |
| pages: | 512-517 |
| ISSN: |
0032-3772 |
| eISSN: |
1897-9483 |
| DOI: | |
| language: | English |
| journal language: | English |
| abstract in English: | Lung cancer is the most common cause of cancer‑related death. Accurate and easy‑to‑use prognostic factors are necessary. Increased platelet count might be a potential prognostic factor. We aimed to investigate the relationship between thrombocytosis and stage of lung cancer and to assess the frequency and clinical importance of thrombocytosis in this patient group. We retrospectively analyzed hospital records of consecutive patients with non-small cell lung cancer (NSCLC) who underwent curative‑intent pulmonary resections. Of 323 patients, 285 patients with NSCLC were selected (mean [SD] age, 66.55 [8.52] years; men, 63.86%). Squamous cell carcinoma was diagnosed in 130 patients (45.61%); adenocarcinoma, in 128 (44.91%); large cell carcinoma, in 16 (5.61%); and adenosquamous carcinoma, in 11 (3.86%). The prevalence of preoperative thrombocytosis in the whole sample was 10.18% (n = 29). Anemia was more common in patients with thrombocytosis compared with those without thrombocytosis (65.52% vs 30.08%; P <0.001). Thrombocytosis was found in 22.41% of patients with stage III+IV cancer and in 3.82% of those with stage I (P <0.001). Moreover, in patients with no metastases (N0, M0 according to the 7th edition of the TNM classification), thrombocytosis was more frequent in the group with stage II than in that with stage I cancer (3.85% vs 20.00%; P = 0.002). Thrombocytosis was also more frequent in patients with N2 than with N1 disease (9.76% vs 23.81%; P = 0.09). Thrombocytosis is often observed in patients with NSCLC and is significantly associated with the higher stage of disease. |
| keywords in English: | lung cancer, non-small cell lung cancer, paraneoplastic syndrome, prognostic factors, thrombocytosis |
| departmental parameterization: | 30 |
| affiliation: | Wydział Nauk o Zdrowiu : Instytut Fizjoterapii |
| type: | journal article |
| subtype: | academic paper |
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
