Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland

doi:10.26444/aaem/75940

Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland

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Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland

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dc.contributor.author	Zając, Joanna [SAP20002658]	pl
dc.contributor.author	Gomółka, Ewa [SAP20008191]	pl
dc.contributor.author	Szot, Wojciech [SAP20001581]	pl
dc.date.accessioned	2020-01-17T09:20:34Z
dc.date.available	2020-01-17T09:20:34Z
dc.date.issued	2018	pl
dc.identifier.issn	1232-1966	pl
dc.identifier.uri	https://ruj.uj.edu.pl/xmlui/handle/item/142488
dc.language	eng	pl
dc.rights	Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne 3.0 Polska	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc/3.0/pl/legalcode	*
dc.title	Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland	pl
dc.type	JournalArticle	pl
dc.description.physical	625-629	pl
dc.abstract.en	Introduction. The aim of presented study was comparison of urinary 1-hydroxypyrene concentration among coke plant workers (before and after working week) and among non-exposed individuals from the same area, taking smoking status into consideration. Materials and method. 647 coke plant workers and 206 individuals living in the same area were analysed with respect to urinary 1-OHP concentration and smoking status. Urinary samples were measured using high performance liquid chromatography (HPLC) with fluorescent detection. Concentrations were normalized with respect to creatinine concentration. For workers, two samples were collected before and after working week. Multiple regression was performed to distinguish and quantify the influence of cigarette smoking and occupational PAH exposition on the urinary 1-OHP levels. Results. Average urinary 1-OHP concentration of samples collected before the working week was: 1.07 μg/g; after the working week: 2.36 μg/g and for control: 0.74 μg/g. The samples collected at the beginning of the working week were not suitable for assessment of the workers’ background (non-occupational) exposition. Smoking cigarettes induced a rise in urinary 1-OHP level by 16%, on average (CI: 5% – 28%), and working for a whole working week at the coke plant made urinary 1-OHP levels, on average, 3.21 times higher (CI: 2.91 – 3.54). Conclusions. Working at the coke plant increases significantly urinary 1-OHP concentration in comparison to nonoccupationally exposed individuals, both for samples collected before and after the working week. Smoking remains a significant source of PAHs exposition, despite the fact that occupational exposure is greater. Health promotion programmes should address both the occupational health risks reduction and smoking prevention.	pl
dc.subject.en	1-hydroxypyrene	pl
dc.subject.en	pyrene	pl
dc.subject.en	coke plant	pl
dc.subject.en	cigarettes smoking	pl
dc.description.volume	25	pl
dc.description.number	4	pl
dc.description.points	30	pl
dc.identifier.doi	10.26444/aaem/75940	pl
dc.identifier.eissn	1898-2263	pl
dc.title.journal	Annals of Agricultural and Environmental Medicine	pl
dc.language.container	eng	pl
dc.affiliation	Wydział Lekarski : Zakład Higieny i Dietetyki	pl
dc.affiliation	Wydział Lekarski : Katedra Toksykologii i Chorób Środowiskowych	pl
dc.subtype	Article	pl
dc.rights.original	CC-BY-NC; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0	pl
dc.identifier.project	ROD UJ / OP	pl
dc.cm.id	87499
dc.cm.date	2020-01-07
.pointsMNiSW	[2018 A]: 30