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Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne 3.0 Polska
Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland
Bibliographic description
| title: | Urinary 1-hydroxypyrene in occupationally-exposed and non-exposed individuals in Silesia, Poland |
| author: | Zając Joanna  , Gomółka Ewa , Szot Wojciech
|
| journal title: | Annals of Agricultural and Environmental Medicine |
| volume: | 25 |
| issue: | 4 |
| date of publication : | 2018 |
| pages: | 625-629 |
| ISSN: |
1232-1966 |
| eISSN: |
1898-2263 |
| DOI: | |
| language: | English |
| abstract in English: | Introduction. The aim of presented study was comparison of urinary 1-hydroxypyrene concentration among coke plant workers (before and after working week) and among non-exposed individuals from the same area, taking smoking status into consideration. Materials and method. 647 coke plant workers and 206 individuals living in the same area were analysed with respect to urinary 1-OHP concentration and smoking status. Urinary samples were measured using high performance liquid chromatography (HPLC) with fluorescent detection. Concentrations were normalized with respect to creatinine concentration. For workers, two samples were collected before and after working week. Multiple regression was performed to distinguish and quantify the influence of cigarette smoking and occupational PAH exposition on the urinary 1-OHP levels. Results. Average urinary 1-OHP concentration of samples collected before the working week was: 1.07 μg/g; after the working week: 2.36 μg/g and for control: 0.74 μg/g. The samples collected at the beginning of the working week were not suitable for assessment of the workers’ background (non-occupational) exposition. Smoking cigarettes induced a rise in urinary 1-OHP level by 16%, on average (CI: 5% – 28%), and working for a whole working week at the coke plant made urinary 1-OHP levels, on average, 3.21 times higher (CI: 2.91 – 3.54). Conclusions. Working at the coke plant increases significantly urinary 1-OHP concentration in comparison to nonoccupationally exposed individuals, both for samples collected before and after the working week. Smoking remains a significant source of PAHs exposition, despite the fact that occupational exposure is greater. Health promotion programmes should address both the occupational health risks reduction and smoking prevention. |
| keywords in English: | 1-hydroxypyrene, pyrene, coke plant, cigarettes smoking |
| departmental parameterization: | 30 |
| affiliation: | Wydział Lekarski : Zakład Higieny i Dietetyki, Wydział Lekarski : Katedra Toksykologii i Chorób Środowiskowych |
| type: | journal article |
| subtype: | academic paper |
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne 3.0 Polska
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
