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Impact of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis

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Impact of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis

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dc.contributor.author Tokarek, Tomasz [SAP20018717] pl
dc.contributor.author Dziewierz, Artur [SAP20011458] pl
dc.contributor.author Wiktorowicz, Agata pl
dc.contributor.author Bagienski, Maciej pl
dc.contributor.author Rzeszutko, Łukasz pl
dc.contributor.author Sorysz, Danuta pl
dc.contributor.author Kleczyński, Paweł [SAP20010977] pl
dc.contributor.author Dudek, Dariusz [SAP20001398] pl
dc.date.accessioned 2020-01-17T09:17:49Z
dc.date.available 2020-01-17T09:17:49Z
dc.date.issued 2018 pl
dc.identifier.issn 1109-9666 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/141274
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Impact of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis pl
dc.type JournalArticle pl
dc.description.physical 100-107 pl
dc.abstract.en Background: Diabetes mellitus (DM) is considered a marker of poor prognosis after cardiac surgery. We sought to investigate the effect of DM on clinical outcomes and quality of life (QoL) after transcatheter aortic valve implantation (TAVI). Methods: A total of 148 consecutive patients with symptomatic, severe aortic stenosis who underwent TAVI were included. Baseline characteristics, procedural and long-term clinical outcomes, and the results of frailty and QoL assessment with EQ-5D-3L questionnaire were compared between patients with and without DM. Results: DM was present in 48 of 148 (32.4%) patients. No differences in periprocedural risk (Logistic Euroscore and Society of Thoracic Surgeons (STS) scale) between groups were observed. There were no differences in 30-day and 12-month all-cause mortality between groups [DM( ) vs. DM(þ): 7 (7.0%) vs. 5 (10.4%), p Z 0.53 and 12 (12.0%) vs. 10 (20.8%), p Z 0.16, respectively]. No influence of DM presence on the risk of death was confirmed after adjustment for age and gender (for 30-day mortality, age/gender-adjusted OR 1.55, 95%CI 0.47 e5.17; for 12-month mortality, age/gender-adjusted OR 2.05, 95%CI 0.79e5.32). Similarly, at the longest available follow-up, mortality did not differ between groups [14 (29.2%) vs. 19 (19.0%), p Z 0.16; age/gender-adjusted OR 1.81, 95%CI 0.80e4.08]. Similar rates of other complications after TAVI were noted. Frailty measured with the 5-meter walking test was more frequently reported in patients with DM [11 (22.9%) vs. 10 (10.0%), p Z 0.035]. No differences in QoL parameters at baseline and 12 months were noted. Conclusions: Patients with DM undergoing TAVI demonstrated similar mortality, complication rates, and QoL outcomes compared to patients without DM pl
dc.subject.en frailty pl
dc.subject.en transcatheter aortic valve replacement pl
dc.subject.en aortic valve disease pl
dc.subject.en high-risk patients pl
dc.subject.en registry pl
dc.description.volume 59 pl
dc.description.number 2 pl
dc.description.points 20 pl
dc.identifier.doi 10.1016/j.hjc.2017.08.002 pl
dc.identifier.eissn 2241-5955 pl
dc.title.journal Hellenic Journal of Cardiology pl
dc.language.container eng pl
dc.affiliation Wydział Lekarski : Instytut Kardiologii pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-ND; inne; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
dc.cm.id 84836
dc.cm.date 2020-01-07
.pointsMNiSW [2018 A]: 20


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa