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Endosonography-guided fine needle aspiration in the diagnosis of sarcoidosis : a randomized study

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Endosonography-guided fine needle aspiration in the diagnosis of sarcoidosis : a randomized study

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dc.contributor.author Kocoń, Piotr [SAP20015053] pl
dc.contributor.author Szlubowski, Artur pl
dc.contributor.author Kużdżał, Jarosław [SAP20011888] pl
dc.contributor.author Rudnicka-Sosin, Lucyna pl
dc.contributor.author Ćmiel, Adam pl
dc.contributor.author Soja, Jerzy [SAP20000999] pl
dc.contributor.author Włodarczyk, Janusz [SAP20012307] pl
dc.contributor.author Talar, Piotr pl
dc.contributor.author Smęder, Tomasz pl
dc.contributor.author Gil, Tomasz [SAP20012234] pl
dc.contributor.author Warmus, Janusz pl
dc.contributor.author Tomaszewska, Romana [SAP20000723] pl
dc.date.accessioned 2020-01-17T09:16:36Z
dc.date.available 2020-01-17T09:16:36Z
dc.date.issued 2017 pl
dc.identifier.issn 0032-3772 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/140816
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/pl/legalcode *
dc.title Endosonography-guided fine needle aspiration in the diagnosis of sarcoidosis : a randomized study pl
dc.type JournalArticle pl
dc.description.physical 154-162 pl
dc.abstract.en There are no widely accepted standards for the diagnosis of sarcoidosis. The aim of this study was to assess the relative diagnostic yield of endobronchial ultrasound fine-needle aspiration (EBUS‑FNA) and endoscopic ultrasound fine-needle aspiration (EUS‑FNA), and to compare them with standard diagnostic techniques such as endobronchial biopsy (EBB), transbronchial lung biopsy (TBLB), transbronchial needle aspiration (TBNA), and mediastinoscopy. This was a prospective randomized study including consecutive patients with clinical diagnosis of stage I or II sarcoidosis. EBB, TBLB, and TBNA were performed at baseline in all patients. Subsequently, patients were randomized to group A (EBUS‑FNA) or group B (EUS‑FNA). Next, a crossover control test was performed: all patients with negative results in group A underwent EUS‑FNA and all patients with negative results in group B underwent EBUS‑FNA. If sarcoidosis was not confirmed, mediastinoscopy was performed. We enrolled 106 patients, of whom 100 were available for the final analysis. The overall sensitivity and accuracy of standard endoscopic methods were 64% each. When analyzing each of the standard endoscopic methods separately, the diagnosis was confirmed with EBB in 12 patients (12%), with TBLB in 42 patients (42%), and with TBNA in 44 patients (44%). The sensitivity and accuracy of each endosonographic technique were significantly higher than those of EBB+TBLB+TBNA (P = 0.0112 vs P = 0.0134). The sensitivity and accuracy of EBUS‑FNA and EUS‑FNA are significantly higher than those of standard endoscopic methods. Moreover, the sensitivity and accuracy of EUS‑FNA tend to be higher than those of EBUS‑FNA. pl
dc.subject.en bronchoscopy pl
dc.subject.en endosonograph pl
dc.subject.en mediastinoscopy pl
dc.subject.en sarcoidosis pl
dc.description.volume 127 pl
dc.description.number 3 pl
dc.description.points 30 pl
dc.identifier.doi 10.20452/pamw.3934 pl
dc.identifier.eissn 1897-9483 pl
dc.title.journal Polskie Archiwum Medycyny Wewnętrznej = Polish Archives of Internal Medicine pl
dc.language.container eng pl
dc.affiliation Wydział Lekarski : Klinika Pulmonologii pl
dc.affiliation Wydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnej pl
dc.affiliation Wydział Nauk o Zdrowiu : Instytut Fizjoterapii pl
dc.subtype Article pl
dc.rights.original OTHER; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
dc.cm.id 83242
dc.cm.date 2020-01-07
.pointsMNiSW [2017 A]: 30


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa