Jagiellonian University Repository
Endosonography-guided fine needle aspiration in the diagnosis of sarcoidosis : a randomized study
Communities & Collections
pcg.skipToMenu
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
Endosonography-guided fine needle aspiration in the diagnosis of sarcoidosis : a randomized study
Bibliographic description
| title: | Endosonography-guided fine needle aspiration in the diagnosis of sarcoidosis : a randomized study |
| author: | Kocoń Piotr  , Szlubowski Artur, Kużdżał Jarosław , Rudnicka-Sosin Lucyna, Ćmiel Adam, Soja Jerzy , Włodarczyk Janusz , Talar Piotr, Smęder Tomasz, Gil Tomasz , Warmus Janusz, Tomaszewska Romana
|
| journal title: | Polskie Archiwum Medycyny Wewnętrznej = Polish Archives of Internal Medicine |
| volume: | 127 |
| issue: | 3 |
| date of publication : | 2017 |
| pages: | 154-162 |
| ISSN: |
0032-3772 |
| eISSN: |
1897-9483 |
| DOI: | |
| language: | English |
| journal language: | English |
| abstract in English: | There are no widely accepted standards for the diagnosis of sarcoidosis. The aim of this study was to assess the relative diagnostic yield of endobronchial ultrasound fine-needle aspiration (EBUS‑FNA) and endoscopic ultrasound fine-needle aspiration (EUS‑FNA), and to compare them with standard diagnostic techniques such as endobronchial biopsy (EBB), transbronchial lung biopsy (TBLB), transbronchial needle aspiration (TBNA), and mediastinoscopy. This was a prospective randomized study including consecutive patients with clinical diagnosis of stage I or II sarcoidosis. EBB, TBLB, and TBNA were performed at baseline in all patients. Subsequently, patients were randomized to group A (EBUS‑FNA) or group B (EUS‑FNA). Next, a crossover control test was performed: all patients with negative results in group A underwent EUS‑FNA and all patients with negative results in group B underwent EBUS‑FNA. If sarcoidosis was not confirmed, mediastinoscopy was performed. We enrolled 106 patients, of whom 100 were available for the final analysis. The overall sensitivity and accuracy of standard endoscopic methods were 64% each. When analyzing each of the standard endoscopic methods separately, the diagnosis was confirmed with EBB in 12 patients (12%), with TBLB in 42 patients (42%), and with TBNA in 44 patients (44%). The sensitivity and accuracy of each endosonographic technique were significantly higher than those of EBB+TBLB+TBNA (P = 0.0112 vs P = 0.0134). The sensitivity and accuracy of EBUS‑FNA and EUS‑FNA are significantly higher than those of standard endoscopic methods. Moreover, the sensitivity and accuracy of EUS‑FNA tend to be higher than those of EBUS‑FNA. |
| keywords in English: | bronchoscopy, endosonograph, mediastinoscopy, sarcoidosis |
| departmental parameterization: | 30 |
| affiliation: | Wydział Lekarski : Klinika Pulmonologii, Wydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnej, Wydział Nauk o Zdrowiu : Instytut Fizjoterapii |
| type: | journal article |
| subtype: | academic paper |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
