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Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland

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Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland

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dc.contributor.author Kawalec, Paweł [SAP20002177] pl
dc.contributor.author Stawowczyk, Ewa pl
dc.contributor.author Mossakowska, Małgorzata pl
dc.contributor.author Pilc, Andrzej [SAP20001714] pl
dc.date.accessioned 2020-01-17T09:15:32Z
dc.date.available 2020-01-17T09:15:32Z
dc.date.issued 2017 pl
dc.identifier.issn 1895-5770 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/140348
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/pl/legalcode *
dc.title Disease activity, quality of life, and indirect costs of ulcerative colitis in Poland pl
dc.type JournalArticle pl
dc.description.physical 60-65 pl
dc.abstract.en Introduction: Ulcerative colitis (UC) require expensive, lifelong treatment, which generates huge direct costs and has a significant impact on the quality of life, especially in the active state of the disease. Aim: To assess the indirect costs, health-related quality of life, and clinical characteristics of patients with UC in Poland. Additionally, we investigated the association between activity of UC and productivity loss of patients in a Polish setting. Material and methods: A questionnaire survey was conducted using the Patient Simple Clinical Colitis Activity Index (P-SCCAI) to assess disease activity, as well as the modified Work Productivity and Activity Impairment Questionnaire to assess productivity loss. The quality of life was presented as utility calculated with the EQ-5D-3L questionnaire. Indirect costs were assessed with the Human Capital Approach and were expressed in Polish zlotys (PLN) as well as in euros (€). Correlations were presented using the Spearman coefficient. Results: We performed our analysis based on 202 full questionnaires collected. Mean patient age and age at disease onset were 33.14 years (standard deviation (SD): 9.90) and 26.35 years (SD: 8.89), respectively. The mean P-SCCAI score in the analysed group of patients was 8.26, and the mean utility was 0.8651. Average and median annual indirect costs per working person were €2043 and €1389 (8543 PLN and 5808 PLN), respectively, calculated using the gross domestic product, as well as €4791 and €3257 (20,026 PLN and 13,615 PLN), respectively, calculated using the gross value added. Total productivity loss was significantly correlated with the disease activity. Conclusions: Ulcerative colitis causes a decrease in the quality of life as well as patients’ productivity loss associated with both absenteeism and with presenteeism. pl
dc.subject.en ulcerative colitis pl
dc.subject.en quality of life pl
dc.subject.en indirect costs pl
dc.subject.en productivity loss pl
dc.description.volume 12 pl
dc.description.number 1 pl
dc.description.points 15 pl
dc.identifier.doi 10.5114/pg.2017.66324 pl
dc.identifier.eissn 1897-4317
dc.title.journal Przegląd Gastroenterologiczny pl
dc.language.container eng pl
dc.affiliation Wydział Nauk o Zdrowiu : Instytut Zdrowia Publicznego pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-SA; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
dc.cm.id 81793
dc.cm.date 2020-01-07
.pointsMNiSW [2017 A]: 15


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa