Prostate, bladder and kidney cancers remain the most common urological
malignancies worldwide, and the prevention and treatment of these diseases pose a challenge to clinicians. In recent decades, many studies have
been conducted to assess the association between supplementation with
selected vitamins and elements and urinary tract tumour initiation and development. Here, we review the relationship between vitamins A, B, D, and
E, in addition to calcium, selenium, and zinc, and the risk of developing
prostate, kidney and bladder cancer. A relatively consistent body of evidence
suggests that large daily doses of calcium (> 2,000 mg/day) increase the
risk of prostate cancer. Similarly, supplementation with 400 IU/day of vitamin E carries a significant risk of prostate cancer. However, there have been
many conflicting results regarding the effect of these nutrients on kidney
and bladder neoplasms. Moreover, the role of other compounds in urinary
tract carcinogenesis needs further clarification.
keywords in English:
vitamins, elements, prostate cancer, kidney cancer, bladder cancer
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