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Progestogens in menopausal hormone therapy

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Progestogens in menopausal hormone therapy

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dc.contributor.author Bińkowska, Małgorzata pl
dc.contributor.author Woroń, Jarosław [SAP20001146] pl
dc.date.accessioned 2020-01-17T08:49:42Z
dc.date.available 2020-01-17T08:49:42Z
dc.date.issued 2015 pl
dc.identifier.issn 1643-8876 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/135771
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/4.0/pl/legalcode *
dc.title Progestogens in menopausal hormone therapy pl
dc.type JournalArticle pl
dc.description.physical 134-143 pl
dc.abstract.en Progestogens share one common effect: the ability to convert proliferative endometrium to its secretory form. In contrast, their biological activity is varied, depending on the chemical structure, pharmacokinetics, receptor affinity and different potency of action. Progestogens are widely used in the treatment of menstrual cycle disturbances, various gynaecological conditions, contraception and menopausal hormone therapy. The administration of progestogen in menopausal hormone therapy is essential in women with an intact uterus to protect against endometrial hyperplasia and cancer. Progestogen selection should be based on the characteristics available for each progestogen type, relying on the assessment of relative potency of action in experimental models and animal models, and on the indirect knowledge brought by studies of the clinical use of different progestogen formulations. The choice of progestogen should involve the conscious use of knowledge of its benefits, with a focus on minimizing potential side effects. Unfortunately, there are no direct clinical studies comparing the metabolic effects of different progestogens. pl
dc.subject.en progestogens pl
dc.subject.en menopausal hormone pl
dc.subject.en therapy pl
dc.subject.en progesterone pl
dc.subject.en progestin pl
dc.description.volume 14 pl
dc.description.number 2 pl
dc.description.points 8 pl
dc.identifier.doi 10.5114/pm.2015.52154 pl
dc.identifier.eissn 2299-0038 pl
dc.title.journal Przegląd Menopauzalny pl
dc.language.container pol pl
dc.affiliation Wydział Lekarski : Zakład Farmakologii Klinicznej pl
dc.subtype ReviewArticle pl
dc.rights.original CC-BY-NC-SA; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
dc.cm.id 73064
dc.cm.date 2020-01-07
.pointsMNiSW [2015 B]: 8


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa