Feasibility and outcomes of early oral feeding after total gastrectomy for cancer
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dc.type
JournalArticle
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dc.description.physical
473-479
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dc.abstract.en
Background Little data are available supporting the feasibility and safety of early oral feeding in patients after total gastrectomy. The aim of this study was to analyze the potential applicability of early provision of oral diet in these settings. Methods Medical records of 353 patients who underwent total gastrectomy for gastric cancer between 2006 and 2012 were retrospectively analyzed. Early oral feeding was defined as clear liquid diet on postoperative day (POD) 1 followed by gradual introduction of solid diet on POD 2 to 3. Late oral feeding was defined as initiation of liquid diet from POD 4 to 6 and gradually advancing to solid diets. Results Early oral feeding was implemented in 185 of 353 (52 %) patients. Prompt provision of food did not increase the risk of anastomotic failure (odds ratio 0.924, 95 % confidence interval 0.609–1.402, P=0.709). The number of reoperations and inhospital mortality rates was unaffected by the timing of nutritional intervention. Early feeding tended to be associated with fewer surgical (15 vs 24 %, P=0.027) and general (8 vs 23 %, P<0.001) complications. However, subsequent multivariate regression models failed to confirm significant correlations between timing of oral meals and postoperative morbidity. Conclusion Our findings suggested that early oral feeding is feasible and safe after total gastrectomy for gastric cancer. However, benefits of such early nutritional interventions require further studies.
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dc.subject.en
gastrectomy
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dc.subject.en
gastric cancer
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dc.subject.en
oral feeding
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dc.subject.en
complications
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dc.subject.en
enhanced recovery after surgery
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dc.description.volume
19
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dc.description.number
3
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dc.description.points
30
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dc.identifier.doi
10.1007/s11605-014-2720-0
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dc.identifier.eissn
1873-4626
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dc.title.journal
Journal of Gastrointestinal Surgery
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dc.language.container
eng
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dc.affiliation
Wydział Lekarski : I Katedra Chirurgii Ogólnej
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dc.affiliation
Wydział Lekarski : Klinika Chirurgii Ogólnej, Onkologicznej i Gastroenterologicznej
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dc.subtype
Article
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dc.rights.original
CC-BY; inne; ostateczna wersja wydawcy; w momencie opublikowania; 0