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Loksapina podawana drogą wziewną : nowa metoda leczenia pobudzenia w psychozach


Loksapina podawana drogą wziewną : nowa metoda leczenia pobudzenia w psychozach

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dc.contributor.author Siwek, Marcin [SAP20010629] pl
dc.date.accessioned 2020-01-17T08:44:48Z
dc.date.available 2020-01-17T08:44:48Z
dc.date.issued 2014 pl
dc.identifier.issn 0033-2674 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/134151
dc.language pol pl
dc.rights Udzielam licencji. Uznanie autorstwa *
dc.rights.uri http://creativecommons.org/licenses *
dc.title Loksapina podawana drogą wziewną : nowa metoda leczenia pobudzenia w psychozach pl
dc.title.alternative Inhaled loxapine : a novel treatment for agitation in psychotic disorders pl
dc.type JournalArticle pl
dc.description.physical 917-930 pl
dc.identifier.weblink http://www.psychiatriapolska.pl/uploads/images/PP_5_2014/917Siwek_PsychiatrPol2014v48i5.pdf pl
dc.identifier.weblink http://www.psychiatriapolska.pl/uploads/images/PP_5_2014/917ENGverSiwek_PsychiatrPol2014v48i5.pdf pl
dc.abstract.en Psychomotor agitation is a widespread clinical problem both in patients with schizophrenia and BD. It is a highly hazardous condition, imposing significant risks in psychiatric emergency, as expressed by elevated ratios of adverse events and traumatic experiences (both for patients and medical staff). The available anti-agitation drugs have numerous disadvantages. The orally administered medications (even though preferable to patients) take hours or even days for the therapeutic effect to emerge (and also there is a risk of exacerbating agitation in between). Although rapid onset of action (15–45 minutes) is a noteworthy merit of intramuscular drugs, such an invasive strategy is far too often bound to patients’ anxiety, resistance, and traumatic experiences. The need for novel drug formulations (ideally, both integrating the benefits of injectable and orally administered tranquillizing medications, and free from their disadvantages) can be, therefore, clearly grasped. Development of inhaled loxapine exemplifies the attempts to overcome the above-delineated obstacles. As suggested by the available research base, inhaled loxapine seems to be an effective anti-agitation drug in treatment of patients with schizophrenia and BD (with the onset of action similar to the one observed in intramuscular antipsychotics). However, this formulation of loxapine is distinguished by its non-invasive route of administration, as accompanied by markedly low risk of side effects or adverse events. pl
dc.subject.pl loksapina pl
dc.subject.pl schizofrenia pl
dc.subject.pl choroba afektywna dwubiegunowa pl
dc.subject.en loxapine pl
dc.subject.en schizophrenia pl
dc.subject.en bipolar disorder pl
dc.description.volume 48 pl
dc.description.number 5 pl
dc.description.points 15 pl
dc.identifier.eissn 2391-5854 pl
dc.title.journal Psychiatria Polska pl
dc.language.container pol pl
dc.date.accession 2019-05-30 pl
dc.affiliation Wydział Lekarski : Zakład Zaburzeń Afektywnych pl
dc.subtype ReviewArticle pl
dc.rights.original CC-BY; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
dc.cm.id 68339
dc.cm.date 2020-01-07
.pointsMNiSW [2014 A]: 15

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Udzielam licencji. Uznanie autorstwa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa