Background and purpose: Falls are common events in Parkinson disease (PD) but only a few prospective studies have
focused on causes and consequences of falls in PD patients.
The aim of the study was prospective analysis of direct causes and consequences of falls in PD patients in comparison to
the control group.
Material and methods: One hundred PD patients and
55 age-matched controls were enrolled in the study. The diagnostic workup in all patients included neurological examination, Unified Parkinson’s Disease Rating Scale, magnetic resonance imaging, electroencephalography, ultrasonography,
otolaryngological, ophthalmological and autonomic function
examination. During 12 months of follow-up, falls were registered in both groups, direct causes were classified according to the St. Louis and Olanow classification, and consequences were established.
Results: Falls occurred in 54% of PD patients and in 18% of
control subjects. Analysis of direct causes of falls revealed that
sudden falls were the most common (31%), followed by
episodes of freezing and festination (19.6%), neurological
and sensory disturbances (mostly vertigo) (12%), environmental factors (12%), postural instability (11%), orthostatic
hypotension (4%), and severe dyskinesia (3.6%); 6.19% of
falls were unclassified; 22% of patients had the same etiology of subsequent falls. In PD patients, intrinsic factors were
dominant, whereas in the control group intrinsic and extrinsic factors occurred with the same frequency. Every third fall
intensified fear of walking. 34% of falls caused injuries;
among them bruises of body parts other than the head were
most frequent.
Conclusions: Intrinsic factors are the most common causes
of falls in PD. Every third fall intensifies fear of walking and
causes injuries.
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