Endolymphatic sac tumour (ELST) is a primary low-grade, locally invasive adenocarcinoma of the endolymphatic sac, characterized
by the proliferation of cuboidal cells forming a papillotubular pattern and colloid-filled cysts. Rare in the general
population, it coincides significantly with the presence of von Hippel-Lindau disease. The natural history, mechanisms underlying
the early symptoms, anatomical origin of ELST and optimal timing of their treatment are unknown. In this study,
we report a Polish male patient with sporadic ELST (without a family history of VHL disease) along with a review of literature.
The light microscopic and immunohistochemical features as well as clinical presentation were typical of ELST.
keywords in English:
endolymphatic sac tumour, ELST, temporal bone, von Hippel-Lindau disease
departmental parameterization:
15
affiliation:
Wydział Lekarski : Zakład Patomorfologii Klinicznej i Doświadczalnej, Wydział Lekarski : Zakład Neuropatologii
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