Repozytorium Uniwersytetu Jagiellońskiego

Raman spectroscopy and the material study of nanocomposite membranes from poly(ε-caprolactone) with biocompatibility testing in osteoblast-like cells

Raman spectroscopy and the material study of ...

Metadane (Dublin Core)

dc.contributor.author Wesełucha-Birczyńska, Aleksandra [SAP11011404] pl
dc.contributor.author Świętek, Małgorzata pl
dc.contributor.author Sołtysiak, Elżbieta pl
dc.contributor.author Galiński, Piotr pl
dc.contributor.author Płachta, Łukasz pl
dc.contributor.author Piekara, Katarzyna pl
dc.contributor.author Błażewicz, M. pl
dc.date.accessioned 2015-07-02T08:00:25Z
dc.date.available 2015-07-02T08:00:25Z
dc.date.issued 2015 pl
dc.identifier.issn 0003-2654 pl
dc.identifier.uri http://ruj.uj.edu.pl/xmlui/handle/item/11125
dc.language eng pl
dc.title Raman spectroscopy and the material study of nanocomposite membranes from poly(ε-caprolactone) with biocompatibility testing in osteoblast-like cells pl
dc.type JournalArticle pl
dc.description.physical 2311-2320 pl
dc.abstract.en Modern medical treatment can be improved by nanotechnology methods for preparing nanocomposites with novel physical, chemical and biological properties. The materials studied and analysed as membranes were produced from poly(ε-caprolactone) (PCL), which contained identical amounts of nano-additives, either montmorillonite (MMT) or functionalized multi-walled carbon nanotubes (MWCNT-f), while the reference membranes were obtained from unmodified PCL. In addition to the conventional methods used in the study of materials for medical purposes such as DSC, contact angle measurements, surface topography, Raman spectroscopy was also applied. Raman microspectroscopy can decode the phenomenon that occurs in the polymer in contact with the nanoparticles. Besides identifying the vibrations of certain functional groups, the calculation of crystallinity parameters is also possible, by which the most intense interactions within the nanocomposites can be analysed. The Raman studies indicate that each of the nano-additives reacts differently with the polymer matrix, which results in material properties that influence its biological properties. MWCNT-f interacts preferentially with the oxygen-containing groups, and particularly with the backbone regions in the vicinity of the single CO bond. The human osteoblast-like MG-63 cells, cultured on the PCL/MWCNT-f membrane for three days, show almost 100% viability. pl
dc.description.volume 140 pl
dc.description.number 7 pl
dc.identifier.doi 10.1039/C4AN02284J pl
dc.identifier.eissn 1364-5528 pl
dc.title.journal Analyst pl
dc.language.container eng pl
dc.affiliation Pion Prorektora ds. badań naukowych i funduszy strukturalnych : CITTRU pl
dc.affiliation Wydział Chemii : Zakład Fizyki Chemicznej pl
dc.subtype Article pl
dc.rights.original bez licencji pl
.pointsMNiSW [2015 A]: 40


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