Comparison of Misoprostol versus Dinoprostone for delivery induction among pregnant women without concomitant disease

2020
journal article
article
dc.abstract.enObjectives: Induction of labour is a part of an active prenatal care nowadays and the ideal method of that procedure still remains to be identified. The purpose of this study was to evaluate effectiveness of misoprostol vaginal insert as compared to dinoprostone gel for delivery induction in pregnant women without any comorbidities. Material and methods: It was a retrospective cohort study of 240 pregnant women. The primary study outcome was successful delivery. Other analysed parameters included time to delivery of a baby, time to the beginning of the first stage of labour, time to vaginal delivery, and duration of all delivery stages. We compared both methods regarding maternal complications during and after delivery. We also reviewed neonatal outcomes such as birth weight, birth length and 1-minute Apgar scores. Results: The patients’ basic characteristics were similar regarding their age, gravidity, parity, height, weight and Bishop score. Time to any delivery and to the onset of a labour in the misoprostol group versus in the dinoprostone group was 14.5 vs 35.6 h (p < 0.001) and 9.9 h vs 25.3 h (p < 0.001) respectively. The chance of the beginning of labour and the baby’s delivery over time has been observed to be approximately two times higher for misoprostol as compared to dinoprostone. Conclusions: Our study showed that using misoprostol vaginal insert in comparison to dinoprostone seems to shorten the time to beginning of the first stage of labour as well as the time to the delivery itself. Some lower Apgar scores observed in the misoprostol group requires further investigation.pl
dc.affiliationWydział Lekarski : Klinika Położnictwa i Perinatologiipl
dc.affiliationWydział Lekarski : Zakład Epidemiologiipl
dc.cm.date2021-03-01
dc.cm.id102651
dc.contributor.authorGornisiewicz, Teresapl
dc.contributor.authorKuśmierska-Urban, Katarzyna - 140799 pl
dc.contributor.authorHuras, Hubert - 129736 pl
dc.contributor.authorGałaś, Aleksander - 129446 pl
dc.date.accessioned2021-03-01T16:50:38Z
dc.date.available2021-03-01T16:50:38Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number12pl
dc.description.physical726-732pl
dc.description.points40
dc.description.versionostateczna wersja wydawcy
dc.description.volume91pl
dc.identifier.doi10.5603/GP.2020.0119pl
dc.identifier.eissn2543-6767pl
dc.identifier.issn0017-0011pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/266130
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enmisoprostolpl
dc.subject.endinoprostonepl
dc.subject.eninduction of laborpl
dc.subtypeArticlepl
dc.titleComparison of Misoprostol versus Dinoprostone for delivery induction among pregnant women without concomitant diseasepl
dc.title.journalGinekologia Polskapl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Objectives: Induction of labour is a part of an active prenatal care nowadays and the ideal method of that procedure still remains to be identified. The purpose of this study was to evaluate effectiveness of misoprostol vaginal insert as compared to dinoprostone gel for delivery induction in pregnant women without any comorbidities. Material and methods: It was a retrospective cohort study of 240 pregnant women. The primary study outcome was successful delivery. Other analysed parameters included time to delivery of a baby, time to the beginning of the first stage of labour, time to vaginal delivery, and duration of all delivery stages. We compared both methods regarding maternal complications during and after delivery. We also reviewed neonatal outcomes such as birth weight, birth length and 1-minute Apgar scores. Results: The patients’ basic characteristics were similar regarding their age, gravidity, parity, height, weight and Bishop score. Time to any delivery and to the onset of a labour in the misoprostol group versus in the dinoprostone group was 14.5 vs 35.6 h (p < 0.001) and 9.9 h vs 25.3 h (p < 0.001) respectively. The chance of the beginning of labour and the baby’s delivery over time has been observed to be approximately two times higher for misoprostol as compared to dinoprostone. Conclusions: Our study showed that using misoprostol vaginal insert in comparison to dinoprostone seems to shorten the time to beginning of the first stage of labour as well as the time to the delivery itself. Some lower Apgar scores observed in the misoprostol group requires further investigation.
dc.affiliationpl
Wydział Lekarski : Klinika Położnictwa i Perinatologii
dc.affiliationpl
Wydział Lekarski : Zakład Epidemiologii
dc.cm.date
2021-03-01
dc.cm.id
102651
dc.contributor.authorpl
Gornisiewicz, Teresa
dc.contributor.authorpl
Kuśmierska-Urban, Katarzyna - 140799
dc.contributor.authorpl
Huras, Hubert - 129736
dc.contributor.authorpl
Gałaś, Aleksander - 129446
dc.date.accessioned
2021-03-01T16:50:38Z
dc.date.available
2021-03-01T16:50:38Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
12
dc.description.physicalpl
726-732
dc.description.points
40
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
91
dc.identifier.doipl
10.5603/GP.2020.0119
dc.identifier.eissnpl
2543-6767
dc.identifier.issnpl
0017-0011
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/266130
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
misoprostol
dc.subject.enpl
dinoprostone
dc.subject.enpl
induction of labor
dc.subtypepl
Article
dc.titlepl
Comparison of Misoprostol versus Dinoprostone for delivery induction among pregnant women without concomitant disease
dc.title.journalpl
Ginekologia Polska
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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