The effects of tobacco smoke exposure on caffeine metabolism

2013
journal article
article
dc.abstract.enCaffeine and nicotine are some of the most often self-administered substances worldwide. Very often they are taken simultaneously and it seems that this fact is correlated with the amount of caffeine and nicotine administered. The aim of this study is to determine, whether tobacco smoke influences the metabolism of caffeine. The secondary task is to establish whether caffeine has an effect on elimination of cotinine, nicotine’s main metabolite. The results showed that tobacco smoke influences the metabolism of caffeine by accelerating its elimination, by the means of induced CYP1A2 activity. As far as cotinine is concerned, no influence of caffeine on its elimination was observed.pl
dc.affiliationWydział Chemii : Zakład Chemii Analitycznejpl
dc.affiliationWydział Lekarski : Katedra Toksykologii i Chorób Środowiskowychpl
dc.contributor.authorGrela, Agatha - 107494 pl
dc.contributor.authorKulza, Maksymilianpl
dc.contributor.authorPiekoszewski, Wojciech - 160149 pl
dc.contributor.authorSeńczuk-Przybyłowska, Monikapl
dc.contributor.authorGomółka, Ewa - 129556 pl
dc.contributor.authorFlorek, Ewapl
dc.date.accessioned2015-01-27T14:15:44Z
dc.date.available2015-01-27T14:15:44Z
dc.date.issued2013pl
dc.description.number1pl
dc.description.physical76-82pl
dc.description.points15pl
dc.description.volume25pl
dc.identifier.eissn2239-5687pl
dc.identifier.issn1120-1770pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/2773
dc.languageengpl
dc.language.containerengpl
dc.rights.licencebez licencji
dc.subject.encaffeinepl
dc.subject.encotininepl
dc.subject.enmetabolismpl
dc.subject.entobacco smokepl
dc.subtypeArticlepl
dc.titleThe effects of tobacco smoke exposure on caffeine metabolismpl
dc.title.journalItalian Journal of Food Sciencepl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Caffeine and nicotine are some of the most often self-administered substances worldwide. Very often they are taken simultaneously and it seems that this fact is correlated with the amount of caffeine and nicotine administered. The aim of this study is to determine, whether tobacco smoke influences the metabolism of caffeine. The secondary task is to establish whether caffeine has an effect on elimination of cotinine, nicotine’s main metabolite. The results showed that tobacco smoke influences the metabolism of caffeine by accelerating its elimination, by the means of induced CYP1A2 activity. As far as cotinine is concerned, no influence of caffeine on its elimination was observed.
dc.affiliationpl
Wydział Chemii : Zakład Chemii Analitycznej
dc.affiliationpl
Wydział Lekarski : Katedra Toksykologii i Chorób Środowiskowych
dc.contributor.authorpl
Grela, Agatha - 107494
dc.contributor.authorpl
Kulza, Maksymilian
dc.contributor.authorpl
Piekoszewski, Wojciech - 160149
dc.contributor.authorpl
Seńczuk-Przybyłowska, Monika
dc.contributor.authorpl
Gomółka, Ewa - 129556
dc.contributor.authorpl
Florek, Ewa
dc.date.accessioned
2015-01-27T14:15:44Z
dc.date.available
2015-01-27T14:15:44Z
dc.date.issuedpl
2013
dc.description.numberpl
1
dc.description.physicalpl
76-82
dc.description.pointspl
15
dc.description.volumepl
25
dc.identifier.eissnpl
2239-5687
dc.identifier.issnpl
1120-1770
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/2773
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights.licence
bez licencji
dc.subject.enpl
caffeine
dc.subject.enpl
cotinine
dc.subject.enpl
metabolism
dc.subject.enpl
tobacco smoke
dc.subtypepl
Article
dc.titlepl
The effects of tobacco smoke exposure on caffeine metabolism
dc.title.journalpl
Italian Journal of Food Science
dc.typepl
JournalArticle
dspace.entity.type
Publication

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