The value of high-resolution MRI technique in patients with rectal carcinoma : pre-operative assessment of mesorectal fascia involvement, circumferential resection margin and local staging

2015
journal article
article
dc.abstract.otherBackground: The purpose of the study was to identify the accuracy of high-resolution MRI in the pre-operative assessment of mesorectal fascia involvement, circumfrential resection margin (CRM) and local staging in patients with rectal carcinoma. Material and Methods: The study included 56 patients: 32 male and 24 female. All patients underwent high-resolution MRI and had confirmed histopathological diagnosis of rectal cancer located within 15 cm from the anal verge, followed by surgery. MRI findings were compared with pathological and surgical results. Results: The overall accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MRI-based T-staging were 92.8, 88.8%, 96.5%, 96%, and 90.3%, respectively. The accuracy, sensitivity, specificity, PPV, and NPV of MRI-based assessment of CRM were 94.6%, 84.6%, 97.6%, 91.4, and 94.6%, respectively. The accuracy, sensitivity, specificity, PPV, and NPV of MRI-based N-staging were 82.1%, 75%, 67.3%, 60%, and 86.1%, respectively. Conclusions: Preoperative high-resolution rectal MRI is accurate in predicting tumor stage and CRM involvement. MRI is a precise diagnostic tool to select patients who may benefit from neo-adjuvant therapy and to avoid overtreatment in those patients who can proceed directly to surgery.pl
dc.contributor.authorAlgebally, Ahmed Mohamedpl
dc.contributor.authorMohey, Nesreenpl
dc.contributor.authorSzmigielski, Wojciechpl
dc.contributor.authorYousef, Reda Ramadan Husseinpl
dc.contributor.authorKohla, Samahpl
dc.date.accessioned2017-07-11T06:58:41Z
dc.date.available2017-07-11T06:58:41Z
dc.date.issued2015pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 121pl
dc.description.physical115-121pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume80pl
dc.identifier.doi10.12659/PJR.892583pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/42597
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode*
dc.share.typeotwarte czasopismo
dc.subject.enmagnetic resonance imagingpl
dc.subject.enneoplasm stagingpl
dc.subject.enrectal neoplasmspl
dc.subtypeArticlepl
dc.titleThe value of high-resolution MRI technique in patients with rectal carcinoma : pre-operative assessment of mesorectal fascia involvement, circumferential resection margin and local stagingpl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.otherpl
Background: The purpose of the study was to identify the accuracy of high-resolution MRI in the pre-operative assessment of mesorectal fascia involvement, circumfrential resection margin (CRM) and local staging in patients with rectal carcinoma. Material and Methods: The study included 56 patients: 32 male and 24 female. All patients underwent high-resolution MRI and had confirmed histopathological diagnosis of rectal cancer located within 15 cm from the anal verge, followed by surgery. MRI findings were compared with pathological and surgical results. Results: The overall accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MRI-based T-staging were 92.8, 88.8%, 96.5%, 96%, and 90.3%, respectively. The accuracy, sensitivity, specificity, PPV, and NPV of MRI-based assessment of CRM were 94.6%, 84.6%, 97.6%, 91.4, and 94.6%, respectively. The accuracy, sensitivity, specificity, PPV, and NPV of MRI-based N-staging were 82.1%, 75%, 67.3%, 60%, and 86.1%, respectively. Conclusions: Preoperative high-resolution rectal MRI is accurate in predicting tumor stage and CRM involvement. MRI is a precise diagnostic tool to select patients who may benefit from neo-adjuvant therapy and to avoid overtreatment in those patients who can proceed directly to surgery.
dc.contributor.authorpl
Algebally, Ahmed Mohamed
dc.contributor.authorpl
Mohey, Nesreen
dc.contributor.authorpl
Szmigielski, Wojciech
dc.contributor.authorpl
Yousef, Reda Ramadan Hussein
dc.contributor.authorpl
Kohla, Samah
dc.date.accessioned
2017-07-11T06:58:41Z
dc.date.available
2017-07-11T06:58:41Z
dc.date.issuedpl
2015
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 121
dc.description.physicalpl
115-121
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
80
dc.identifier.doipl
10.12659/PJR.892583
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/42597
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode
dc.share.type
otwarte czasopismo
dc.subject.enpl
magnetic resonance imaging
dc.subject.enpl
neoplasm staging
dc.subject.enpl
rectal neoplasms
dc.subtypepl
Article
dc.titlepl
The value of high-resolution MRI technique in patients with rectal carcinoma : pre-operative assessment of mesorectal fascia involvement, circumferential resection margin and local staging
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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