Adrenocortical carcinoma in preoperative diagnostic imaging

2006
journal article
article
dc.abstract.enBackground: Decisions concerning surgical treatment of patients with adrenocortical tumor without hormonal hyperactivity are based on tumor size exceeding 3-6 cm and morphological features of malignancy. The aim of the study was to analyze results of diagnostic imaging in patients with adrenocortical carcinoma (ACC). Material/Methods: Results of diagnostic imaging of 8 patients in whom postoperative pathological examination revealed ACC were analyzed. There were 3 women and 5 men in the analyzed group, with an age range of 32 to 75 years. Imaging was based on US and CT examination supported by MRI in 2 patients. The obtained results were compared with a group of 10 patients with adrenocortical adenoma (ACA). Results are presented as median values and 95% CI. Results: CT results of patients with ACC showed local spread into surrounding fat tissue in 87.5%, adjacent organ invasion in 75%, local lymph node enlargement in 75%, irregular tumor margins in 88%, and heterogeneous structure of all tumors. In patients with ACA, tumor heterogeneity was observed in 40% and local lymph node enlargement in 10%. ACC tumors were significantly larger than ACA ones [77 (66-97) vs. 31 (24-48) mm, respectively, p=0.0002] and more dense [60 (34-85) vs. 16 (10-26) HU, respectively, p=0.0007]. In arterial phase, enhancement of ACC tumors tended to be stronger compared with ACA [81 (29-162) vs. 55 (33-76), p=0.09]. On the basis of CT results, 1 patient was classified as stage II according to Mac Farlane, 6 as stage III, and 1 as stage IV. Intraoperative examination down-staged 2 patients from stage III to stage II. Conclusions: Computed tomography is a method that allows distinguishing adrenocortical adenoma from carcinoma as well as to determine the stage of adrenocortical carcinoma.pl
dc.contributor.authorZiaja, Jacekpl
dc.contributor.authorHartel, Marcinpl
dc.contributor.authorKról, Robertpl
dc.contributor.authorKiełtyka, Aleksandrapl
dc.contributor.authorKonopka, Marekpl
dc.contributor.authorBadura, Joannapl
dc.contributor.authorKajor, Maciejpl
dc.contributor.authorWięcek, Andrzejpl
dc.contributor.authorGasińska, Teresapl
dc.contributor.authorCierpka, Lechpl
dc.date.accession2019-08-16pl
dc.date.accessioned2019-08-16T07:10:56Z
dc.date.available2019-08-16T07:10:56Z
dc.date.issued2006pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 35pl
dc.description.number3pl
dc.description.physical8-35pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume71pl
dc.identifier.articleid456363pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/80814
dc.identifier.weblinkhttp://archiwum.inforadiologia.pl/download/index/idArt/456363.htmlpl
dc.languagepolpl
dc.language.containerpolpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enadrenocortical carcinomapl
dc.subject.enadrenocortical adenomapl
dc.subject.endiagnostic imagingpl
dc.subject.encomputed tomographypl
dc.subtypeArticlepl
dc.titleAdrenocortical carcinoma in preoperative diagnostic imagingpl
dc.title.alternativeRak kory nadnerczy w przedoperacyjnych badaniach obrazowychpl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Background: Decisions concerning surgical treatment of patients with adrenocortical tumor without hormonal hyperactivity are based on tumor size exceeding 3-6 cm and morphological features of malignancy. The aim of the study was to analyze results of diagnostic imaging in patients with adrenocortical carcinoma (ACC). Material/Methods: Results of diagnostic imaging of 8 patients in whom postoperative pathological examination revealed ACC were analyzed. There were 3 women and 5 men in the analyzed group, with an age range of 32 to 75 years. Imaging was based on US and CT examination supported by MRI in 2 patients. The obtained results were compared with a group of 10 patients with adrenocortical adenoma (ACA). Results are presented as median values and 95% CI. Results: CT results of patients with ACC showed local spread into surrounding fat tissue in 87.5%, adjacent organ invasion in 75%, local lymph node enlargement in 75%, irregular tumor margins in 88%, and heterogeneous structure of all tumors. In patients with ACA, tumor heterogeneity was observed in 40% and local lymph node enlargement in 10%. ACC tumors were significantly larger than ACA ones [77 (66-97) vs. 31 (24-48) mm, respectively, p=0.0002] and more dense [60 (34-85) vs. 16 (10-26) HU, respectively, p=0.0007]. In arterial phase, enhancement of ACC tumors tended to be stronger compared with ACA [81 (29-162) vs. 55 (33-76), p=0.09]. On the basis of CT results, 1 patient was classified as stage II according to Mac Farlane, 6 as stage III, and 1 as stage IV. Intraoperative examination down-staged 2 patients from stage III to stage II. Conclusions: Computed tomography is a method that allows distinguishing adrenocortical adenoma from carcinoma as well as to determine the stage of adrenocortical carcinoma.
dc.contributor.authorpl
Ziaja, Jacek
dc.contributor.authorpl
Hartel, Marcin
dc.contributor.authorpl
Król, Robert
dc.contributor.authorpl
Kiełtyka, Aleksandra
dc.contributor.authorpl
Konopka, Marek
dc.contributor.authorpl
Badura, Joanna
dc.contributor.authorpl
Kajor, Maciej
dc.contributor.authorpl
Więcek, Andrzej
dc.contributor.authorpl
Gasińska, Teresa
dc.contributor.authorpl
Cierpka, Lech
dc.date.accessionpl
2019-08-16
dc.date.accessioned
2019-08-16T07:10:56Z
dc.date.available
2019-08-16T07:10:56Z
dc.date.issuedpl
2006
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 35
dc.description.numberpl
3
dc.description.physicalpl
8-35
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
71
dc.identifier.articleidpl
456363
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/80814
dc.identifier.weblinkpl
http://archiwum.inforadiologia.pl/download/index/idArt/456363.html
dc.languagepl
pol
dc.language.containerpl
pol
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
adrenocortical carcinoma
dc.subject.enpl
adrenocortical adenoma
dc.subject.enpl
diagnostic imaging
dc.subject.enpl
computed tomography
dc.subtypepl
Article
dc.titlepl
Adrenocortical carcinoma in preoperative diagnostic imaging
dc.title.alternativepl
Rak kory nadnerczy w przedoperacyjnych badaniach obrazowych
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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