The relationship between FDG PET/CT-defined metabolic parameters and the histopathological subtype of oesophageal carcinomas

2020
journal article
article
cris.lastimport.wos2024-04-09T22:25:42Z
dc.abstract.enPurpose: 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) combined with computed tomography (CT) scan is accepted as a standard tool in the staging of oesophageal cancer (OC). Histological subtype of tumour is known to be a major determinant of prognosis and metabolic behaviour. In this study, we aimed to evaluate the effect of histological subtypes of OC on standard uptake value (SUVmax), metabolic tumour volume (MTV), and total lesion glycolysis (TLG) obtained by PET/CT, and also to compare this effect with prognosis. Material and methods: Images and clinical course data of 57 patients who were diagnosed with EC and treated in our hospital between 2009 and 2016 were evaluated in a retrospective manner. PET/CT images were re-analysed in terms of metabolic parameters, and observations were compared with histological subtypes. Results: No significant difference was observed between histological subtypes with SUVmax, overall survival (OS), or progression-free survival (PFS). Thus, MTV was observed to be related with histological subtype; MTV values of adenocancer patients were significantly higher than those of squamous cell cancer patients. Conclusions: Metabolic tumour volume was related with histological subtype of OC, but clinical staging, TLG, and SUVmax values were not related with histological subtype, which may suggest the use of MTV as a routine parameter for OC and inclusion of MTV observations in prognostic scoring.pl
dc.contributor.authorKorkmaz, Ulkupl
dc.contributor.authorBekir Hacioglu, Muhammetpl
dc.contributor.authorKostek, Osmanpl
dc.contributor.authorSut, Necdetpl
dc.contributor.authorKodaz, Hilmipl
dc.contributor.authorErdogan, Bulentpl
dc.contributor.authorUstun, Fundapl
dc.contributor.authorSaynak, Mertpl
dc.contributor.authorTastekin, Ebrupl
dc.contributor.authorCicin, Irfanpl
dc.contributor.authorDurmus-Altun, Gulaypl
dc.date.accessioned2020-07-08T10:55:29Z
dc.date.available2020-07-08T10:55:29Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e259-e260pl
dc.description.physicale254-e260pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume85pl
dc.identifier.doi10.5114/pjr.2020.95945pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/165458
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enoesophageal cancerpl
dc.subject.enPET/CTpl
dc.subject.ensquamous cell cancerpl
dc.subject.enSUVmaxpl
dc.subject.enMTVpl
dc.subject.enTLGpl
dc.subtypeArticlepl
dc.titleThe relationship between FDG PET/CT-defined metabolic parameters and the histopathological subtype of oesophageal carcinomaspl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T22:25:42Z
dc.abstract.enpl
Purpose: 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) combined with computed tomography (CT) scan is accepted as a standard tool in the staging of oesophageal cancer (OC). Histological subtype of tumour is known to be a major determinant of prognosis and metabolic behaviour. In this study, we aimed to evaluate the effect of histological subtypes of OC on standard uptake value (SUVmax), metabolic tumour volume (MTV), and total lesion glycolysis (TLG) obtained by PET/CT, and also to compare this effect with prognosis. Material and methods: Images and clinical course data of 57 patients who were diagnosed with EC and treated in our hospital between 2009 and 2016 were evaluated in a retrospective manner. PET/CT images were re-analysed in terms of metabolic parameters, and observations were compared with histological subtypes. Results: No significant difference was observed between histological subtypes with SUVmax, overall survival (OS), or progression-free survival (PFS). Thus, MTV was observed to be related with histological subtype; MTV values of adenocancer patients were significantly higher than those of squamous cell cancer patients. Conclusions: Metabolic tumour volume was related with histological subtype of OC, but clinical staging, TLG, and SUVmax values were not related with histological subtype, which may suggest the use of MTV as a routine parameter for OC and inclusion of MTV observations in prognostic scoring.
dc.contributor.authorpl
Korkmaz, Ulku
dc.contributor.authorpl
Bekir Hacioglu, Muhammet
dc.contributor.authorpl
Kostek, Osman
dc.contributor.authorpl
Sut, Necdet
dc.contributor.authorpl
Kodaz, Hilmi
dc.contributor.authorpl
Erdogan, Bulent
dc.contributor.authorpl
Ustun, Funda
dc.contributor.authorpl
Saynak, Mert
dc.contributor.authorpl
Tastekin, Ebru
dc.contributor.authorpl
Cicin, Irfan
dc.contributor.authorpl
Durmus-Altun, Gulay
dc.date.accessioned
2020-07-08T10:55:29Z
dc.date.available
2020-07-08T10:55:29Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e259-e260
dc.description.physicalpl
e254-e260
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
85
dc.identifier.doipl
10.5114/pjr.2020.95945
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/165458
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
oesophageal cancer
dc.subject.enpl
PET/CT
dc.subject.enpl
squamous cell cancer
dc.subject.enpl
SUVmax
dc.subject.enpl
MTV
dc.subject.enpl
TLG
dc.subtypepl
Article
dc.titlepl
The relationship between FDG PET/CT-defined metabolic parameters and the histopathological subtype of oesophageal carcinomas
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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