Hepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state in Ile-Ife, Nigeria

2017
journal article
article
5
cris.lastimport.wos2024-04-10T00:28:04Z
dc.abstract.plBACKGROUND: Sickle cell anaemia (SCA) is associated with structural manifestations in the hepatobiliary axis. This study aimed to investigate the hepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state attending the Haematology clinic of a federal tertiary health institution in Ile-Ife, Nigeria. MATERIAL AND METHODS: Basic demographic data as well as right upper abdominal quadrant ultrasonography of 50 consecutive sickle cell anaemia patients were compared with those of 50 age- and sex-matched subjects with HbAA as controls. RESULTS: Each of the study groups (patients and controls) comprised of 21 (42%) males and 29 (58%) females. The age range of the patients was 18-45 years with a mean (±SD) of 27.6±7.607 years, while that of the controls was 21-43 years with a mean (±SD) of 28.0±5.079 years (p=0.746). Amongst the patients, 32 (64%) had hepatomegaly, 15 (30%) cholelithiasis and 3 (6%) biliary sludge. Fourteen (28%) of the patients had normal hepatobiliary ultrasound findings. In the control group, one (2%) person had cholelithiasis, one (2%) biliary sludge, one (2%) fatty liver and none hepatomegaly. Forty-seven (94%) of the controls had normal hepatobiliary ultrasound findings. There was a statistically significant difference in the prevalence of hepatomegaly and cholelithiasis between the patients and controls (p value <0.001 for both comparisons). CONCLUSIONS: In this study, hepatomegaly, cholelithiasis and biliary sludge were the most common hepatobiliary ultrasound findings in patients with sickle cell anaemia. Ultrasonography is a useful tool for assessing hepatobiliary abnormalities in patients with sickle cell anaemia.pl
dc.contributor.authorOguntoye, Oluwatosin O.pl
dc.contributor.authorNdububa, Dennis A.pl
dc.contributor.authorYusuf, Musahpl
dc.contributor.authorBolarinwa, Rahman A.pl
dc.contributor.authorAyoola, Oluwagbemiga O.pl
dc.date.accessioned2017-02-27T10:01:10Z
dc.date.available2017-02-27T10:01:10Z
dc.date.issued2017pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 7-8pl
dc.description.physical1-8pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume82pl
dc.identifier.doi10.12659/PJR.899609pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/38908
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode*
dc.share.typeotwarte czasopismo
dc.subject.enabnormalitiespl
dc.subject.enmultiplepl
dc.subject.enanemiapl
dc.subject.ensickle cellpl
dc.subject.enultrasonographypl
dc.subtypeArticlepl
dc.titleHepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state in Ile-Ife, Nigeriapl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T00:28:04Z
dc.abstract.plpl
BACKGROUND: Sickle cell anaemia (SCA) is associated with structural manifestations in the hepatobiliary axis. This study aimed to investigate the hepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state attending the Haematology clinic of a federal tertiary health institution in Ile-Ife, Nigeria. MATERIAL AND METHODS: Basic demographic data as well as right upper abdominal quadrant ultrasonography of 50 consecutive sickle cell anaemia patients were compared with those of 50 age- and sex-matched subjects with HbAA as controls. RESULTS: Each of the study groups (patients and controls) comprised of 21 (42%) males and 29 (58%) females. The age range of the patients was 18-45 years with a mean (±SD) of 27.6±7.607 years, while that of the controls was 21-43 years with a mean (±SD) of 28.0±5.079 years (p=0.746). Amongst the patients, 32 (64%) had hepatomegaly, 15 (30%) cholelithiasis and 3 (6%) biliary sludge. Fourteen (28%) of the patients had normal hepatobiliary ultrasound findings. In the control group, one (2%) person had cholelithiasis, one (2%) biliary sludge, one (2%) fatty liver and none hepatomegaly. Forty-seven (94%) of the controls had normal hepatobiliary ultrasound findings. There was a statistically significant difference in the prevalence of hepatomegaly and cholelithiasis between the patients and controls (p value <0.001 for both comparisons). CONCLUSIONS: In this study, hepatomegaly, cholelithiasis and biliary sludge were the most common hepatobiliary ultrasound findings in patients with sickle cell anaemia. Ultrasonography is a useful tool for assessing hepatobiliary abnormalities in patients with sickle cell anaemia.
dc.contributor.authorpl
Oguntoye, Oluwatosin O.
dc.contributor.authorpl
Ndububa, Dennis A.
dc.contributor.authorpl
Yusuf, Musah
dc.contributor.authorpl
Bolarinwa, Rahman A.
dc.contributor.authorpl
Ayoola, Oluwagbemiga O.
dc.date.accessioned
2017-02-27T10:01:10Z
dc.date.available
2017-02-27T10:01:10Z
dc.date.issuedpl
2017
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 7-8
dc.description.physicalpl
1-8
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
82
dc.identifier.doipl
10.12659/PJR.899609
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/38908
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode
dc.share.type
otwarte czasopismo
dc.subject.enpl
abnormalities
dc.subject.enpl
multiple
dc.subject.enpl
anemia
dc.subject.enpl
sickle cell
dc.subject.enpl
ultrasonography
dc.subtypepl
Article
dc.titlepl
Hepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state in Ile-Ife, Nigeria
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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