Enzymatic antioxidant systems in early anaerobes : theoretical considerations

2016
journal article
article
42
cris.lastimport.wos2024-04-09T22:27:35Z
dc.abstract.enIt is widely accepted that cyanobacteria-dependent oxygen that was released into Earth's atmosphere ca. 2.5 billion years ago sparked the evolution of the aerobic metabolism and the antioxidant system. In modern aerobes, enzymes such as superoxide dismutases (SODs), peroxiredoxins (PXs), and catalases (CATs) constitute the core of the enzymatic antioxidant system (EAS) directed against reactive oxygen species (ROS). In many anaerobic prokaryotes, the superoxide reductases (SORs) have been identified as the main force in counteracting ROS toxicity. We found that 93% of the analyzed strict anaerobes possess at least one antioxidant enzyme, and 50% have a functional EAS, that is, consisting of at least two antioxidant enzymes: one for superoxide anion radical detoxification and another for hydrogen peroxide decomposition. The results presented here suggest that the last universal common ancestor (LUCA) was not a strict anaerobe. O2 could have been available for the first microorganisms before oxygenic photosynthesis evolved, however, from the intrinsic activity of EAS, not solely from abiotic sources.pl
dc.affiliationWydział Biologii i Nauk o Ziemi : Instytut Nauk o Środowiskupl
dc.affiliationWydział Biologii i Nauk o Ziemi : Instytut Botanikipl
dc.contributor.authorŚlesak, Ireneuszpl
dc.contributor.authorŚlesak, Halina - 132311 pl
dc.contributor.authorZimak-Piekarczyk, Paulinapl
dc.contributor.authorRozpądek, Piotr - 104523 pl
dc.date.accessioned2016-10-07T18:02:57Z
dc.date.available2016-10-07T18:02:57Z
dc.date.issued2016pl
dc.description.number5pl
dc.description.physical348-358pl
dc.description.volume16pl
dc.identifier.doi10.1089/ast.2015.1328pl
dc.identifier.eissn1557-8070pl
dc.identifier.issn1531-1074pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/31258
dc.languageengpl
dc.language.containerengpl
dc.rightsDodaję tylko opis bibliograficzny*
dc.rights.licencebez licencji
dc.rights.uri*
dc.subject.enArchaeapl
dc.subject.enAtmospheric gasespl
dc.subject.enEvolutionpl
dc.subject.enH2O2 resistancepl
dc.subject.enOxygenic photosynthesispl
dc.subtypeArticlepl
dc.titleEnzymatic antioxidant systems in early anaerobes : theoretical considerationspl
dc.title.journalAstrobiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T22:27:35Z
dc.abstract.enpl
It is widely accepted that cyanobacteria-dependent oxygen that was released into Earth's atmosphere ca. 2.5 billion years ago sparked the evolution of the aerobic metabolism and the antioxidant system. In modern aerobes, enzymes such as superoxide dismutases (SODs), peroxiredoxins (PXs), and catalases (CATs) constitute the core of the enzymatic antioxidant system (EAS) directed against reactive oxygen species (ROS). In many anaerobic prokaryotes, the superoxide reductases (SORs) have been identified as the main force in counteracting ROS toxicity. We found that 93% of the analyzed strict anaerobes possess at least one antioxidant enzyme, and 50% have a functional EAS, that is, consisting of at least two antioxidant enzymes: one for superoxide anion radical detoxification and another for hydrogen peroxide decomposition. The results presented here suggest that the last universal common ancestor (LUCA) was not a strict anaerobe. O2 could have been available for the first microorganisms before oxygenic photosynthesis evolved, however, from the intrinsic activity of EAS, not solely from abiotic sources.
dc.affiliationpl
Wydział Biologii i Nauk o Ziemi : Instytut Nauk o Środowisku
dc.affiliationpl
Wydział Biologii i Nauk o Ziemi : Instytut Botaniki
dc.contributor.authorpl
Ślesak, Ireneusz
dc.contributor.authorpl
Ślesak, Halina - 132311
dc.contributor.authorpl
Zimak-Piekarczyk, Paulina
dc.contributor.authorpl
Rozpądek, Piotr - 104523
dc.date.accessioned
2016-10-07T18:02:57Z
dc.date.available
2016-10-07T18:02:57Z
dc.date.issuedpl
2016
dc.description.numberpl
5
dc.description.physicalpl
348-358
dc.description.volumepl
16
dc.identifier.doipl
10.1089/ast.2015.1328
dc.identifier.eissnpl
1557-8070
dc.identifier.issnpl
1531-1074
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/31258
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Dodaję tylko opis bibliograficzny
dc.rights.licence
bez licencji
dc.rights.uri*
dc.subject.enpl
Archaea
dc.subject.enpl
Atmospheric gases
dc.subject.enpl
Evolution
dc.subject.enpl
H2O2 resistance
dc.subject.enpl
Oxygenic photosynthesis
dc.subtypepl
Article
dc.titlepl
Enzymatic antioxidant systems in early anaerobes : theoretical considerations
dc.title.journalpl
Astrobiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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