Novel eco-friendly tannic acid-enriched hydrogels-preparation and characterization for biomedical application

2020
journal article
article
11
cris.lastimport.wos2024-04-10T02:44:46Z
dc.abstract.enSodium alginate and tannic acid are natural compounds that can be mixed with each other. In this study, we propose novel eco-friendly hydrogels for biomedical applications. Thus, we conducted the following assessments including (i) observation of the structure of hydrogels by scanning electron microscope; (ii) bioerosion and the concentration of released tannic acid from subjected material; (iii) dehydrogenase activity assay to determine antibacterial activity of prepared hydrogels; and (iv) blood and cell compatibility. The results showed that hydrogels based on sodium alginate/tannic acid exert a porous structure. The immersion in simulated body fluid (SBF) results in the biomineralization process occurring on their surface while the bioerosion studies revealed that the addition of tannic acid improves hydrogels’ stability proportional to its concentration. Besides, tannic acid release concentration depends on the type of hydrogels and the highest amount was noticed for those based on sodium alginate with the content of 30% tannic acid. Antibacterial activity of hydrogels was proven for both Gram-negative and Gram-positive bacteria, the hemolysis rate was below 5% and the viability of the cells was elevated with an increasing amount of tannic acid in hydrogels. Collectively, we assume that obtained materials make the imperative to consider them for biomedical applications.pl
dc.affiliationWydział Biologii : Instytut Zoologii i Badań Biomedycznychpl
dc.contributor.authorKaczmarek, Beatapl
dc.contributor.authorMiłek, Oliwiapl
dc.contributor.authorMichalska-Sionkowska, Martapl
dc.contributor.authorZasada, Lidiapl
dc.contributor.authorTwardowska, Martapl
dc.contributor.authorWarżyńska, Oliwiapl
dc.contributor.authorKleszczyński, Konradpl
dc.contributor.authorOsyczka, Anna - 131214 pl
dc.date.accessioned2021-02-09T13:05:46Z
dc.date.available2021-02-09T13:05:46Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number20pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume13pl
dc.identifier.articleid4572pl
dc.identifier.doi10.3390/ma13204572pl
dc.identifier.eissn1996-1944pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/262954
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.entannic acidpl
dc.subject.ensodium alginatepl
dc.subject.enhydrogelpl
dc.subject.enwound dressingspl
dc.subtypeArticlepl
dc.titleNovel eco-friendly tannic acid-enriched hydrogels-preparation and characterization for biomedical applicationpl
dc.title.journalMaterialspl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T02:44:46Z
dc.abstract.enpl
Sodium alginate and tannic acid are natural compounds that can be mixed with each other. In this study, we propose novel eco-friendly hydrogels for biomedical applications. Thus, we conducted the following assessments including (i) observation of the structure of hydrogels by scanning electron microscope; (ii) bioerosion and the concentration of released tannic acid from subjected material; (iii) dehydrogenase activity assay to determine antibacterial activity of prepared hydrogels; and (iv) blood and cell compatibility. The results showed that hydrogels based on sodium alginate/tannic acid exert a porous structure. The immersion in simulated body fluid (SBF) results in the biomineralization process occurring on their surface while the bioerosion studies revealed that the addition of tannic acid improves hydrogels’ stability proportional to its concentration. Besides, tannic acid release concentration depends on the type of hydrogels and the highest amount was noticed for those based on sodium alginate with the content of 30% tannic acid. Antibacterial activity of hydrogels was proven for both Gram-negative and Gram-positive bacteria, the hemolysis rate was below 5% and the viability of the cells was elevated with an increasing amount of tannic acid in hydrogels. Collectively, we assume that obtained materials make the imperative to consider them for biomedical applications.
dc.affiliationpl
Wydział Biologii : Instytut Zoologii i Badań Biomedycznych
dc.contributor.authorpl
Kaczmarek, Beata
dc.contributor.authorpl
Miłek, Oliwia
dc.contributor.authorpl
Michalska-Sionkowska, Marta
dc.contributor.authorpl
Zasada, Lidia
dc.contributor.authorpl
Twardowska, Marta
dc.contributor.authorpl
Warżyńska, Oliwia
dc.contributor.authorpl
Kleszczyński, Konrad
dc.contributor.authorpl
Osyczka, Anna - 131214
dc.date.accessioned
2021-02-09T13:05:46Z
dc.date.available
2021-02-09T13:05:46Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
20
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
13
dc.identifier.articleidpl
4572
dc.identifier.doipl
10.3390/ma13204572
dc.identifier.eissnpl
1996-1944
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/262954
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri*
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
tannic acid
dc.subject.enpl
sodium alginate
dc.subject.enpl
hydrogel
dc.subject.enpl
wound dressings
dc.subtypepl
Article
dc.titlepl
Novel eco-friendly tannic acid-enriched hydrogels-preparation and characterization for biomedical application
dc.title.journalpl
Materials
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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