The role of diffusion tensor imaging in idiopathic sensorineural hearing loss : is it significant?

2021
journal article
article
dc.abstract.enPurpose: To assess the role of diffusion tensor imaging metrics in the evaluation of the microstructural integrity of the central auditory tract in patients with idiopathic sensorineural hearing loss (SNHL), and to compare these patients with healthy controls. Material and methods: This prospective study, which was conducted upon 30 subjects (21 males, 9 females; age range from 16 to 65 years, mean age 45years) with SNHL proven by audiometric tests. Ten age- and sex-matched healthy volunteers were included as a control group. Patients (n = 30) and volunteers (n = 10) underwent conventional magnetic resonance imaging and diffusion tensor imaging of the brain. Both fractional anisotropy and mean diffusivity (MD) of 3 points along the acoustic tract (inferior colliculus, lateral lemniscus and superior olivary nucleus) were measured bilaterally in all patients and correlated with controls. Results: Mean fractional anisotropy (FA) values were reduced bilaterally at the superior olivary nucleus and/or lateral lemniscus and more significantly at the inferior colliculus of subjects with SNHL in comparison to the volunteers. In patients of unilateral SNHL, similar results were obtained in the contralateral side when compared to controls with statistically significant difference at the 3 regions (p = 0.001). No significant changes were noticed in the MD parameters either in patient or control groups. Conclusions: The FA value was a valuable non-invasive biomarker in evaluating the subtle microstructural abnormalities of the central auditory tract in idiopathic SNHL and correlated well with hearing impairment.pl
dc.contributor.authorMahmoud, Walaapl
dc.contributor.authorElshawaf, Wessampl
dc.contributor.authorTawfik, Ahmedpl
dc.date.accessioned2021-09-02T07:28:47Z
dc.date.available2021-09-02T07:28:47Z
dc.date.issued2021pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e479-e480pl
dc.description.physicale474-e480pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume86pl
dc.identifier.doi10.5114/pjr.2021.108372pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/278020
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.endiffusion tensorpl
dc.subject.enidiopathic SNHLpl
dc.subject.encentral auditory pathwaypl
dc.subtypeArticlepl
dc.titleThe role of diffusion tensor imaging in idiopathic sensorineural hearing loss : is it significant?pl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Purpose: To assess the role of diffusion tensor imaging metrics in the evaluation of the microstructural integrity of the central auditory tract in patients with idiopathic sensorineural hearing loss (SNHL), and to compare these patients with healthy controls. Material and methods: This prospective study, which was conducted upon 30 subjects (21 males, 9 females; age range from 16 to 65 years, mean age 45years) with SNHL proven by audiometric tests. Ten age- and sex-matched healthy volunteers were included as a control group. Patients (n = 30) and volunteers (n = 10) underwent conventional magnetic resonance imaging and diffusion tensor imaging of the brain. Both fractional anisotropy and mean diffusivity (MD) of 3 points along the acoustic tract (inferior colliculus, lateral lemniscus and superior olivary nucleus) were measured bilaterally in all patients and correlated with controls. Results: Mean fractional anisotropy (FA) values were reduced bilaterally at the superior olivary nucleus and/or lateral lemniscus and more significantly at the inferior colliculus of subjects with SNHL in comparison to the volunteers. In patients of unilateral SNHL, similar results were obtained in the contralateral side when compared to controls with statistically significant difference at the 3 regions (p = 0.001). No significant changes were noticed in the MD parameters either in patient or control groups. Conclusions: The FA value was a valuable non-invasive biomarker in evaluating the subtle microstructural abnormalities of the central auditory tract in idiopathic SNHL and correlated well with hearing impairment.
dc.contributor.authorpl
Mahmoud, Walaa
dc.contributor.authorpl
Elshawaf, Wessam
dc.contributor.authorpl
Tawfik, Ahmed
dc.date.accessioned
2021-09-02T07:28:47Z
dc.date.available
2021-09-02T07:28:47Z
dc.date.issuedpl
2021
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e479-e480
dc.description.physicalpl
e474-e480
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
86
dc.identifier.doipl
10.5114/pjr.2021.108372
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/278020
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
diffusion tensor
dc.subject.enpl
idiopathic SNHL
dc.subject.enpl
central auditory pathway
dc.subtypepl
Article
dc.titlepl
The role of diffusion tensor imaging in idiopathic sensorineural hearing loss : is it significant?
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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