The effect of physical activity on cytokine levels in adults living with type 1 diabetes : a preliminary study

2024
journal article
article
dc.abstract.enThe aim of this study is to investigate whether physical activity and the level of body fat are factors reducing the level of pro-inflammatory cytokines in people with T1DM. Twenty-five men (27.8 ± 9.4 years old; 178.9 ± 6.9 cm; 80.6 ± 12 kg) and 18 women (28.1 ± 12.5 years old; 162.4 ± 5.5; 63.1 ± 9.9 kg) were divided into four groups based on body fat percentage and level of physical activity (AN—active people with normal body fat; IAN—inactive people with normal body fat; AO—active people with excessive body fat, IAO—inactive people with excessive body fat). The level of cytokines in the blood serum was assessed. The level of IL-8 was higher (measurable) in inactive men, regardless of adiposity degree and in women, only in the inactive group with normal body fat. IL-6 was found only in active men with excessive adiposity. In conclusion, the findings from this study allow to indicate that moderate level of physical activity may contribute to a reduction in the development of systemic low-grade inflammation in patients with T1DM, and thus, may reduce the risk of CVD.
dc.affiliationWydział Biologii : Instytut Zoologii i Badań Biomedycznych
dc.contributor.authorKowal Małgorzata
dc.contributor.authorWoźniacka Renata
dc.contributor.authorŚcisłowska-Czarnecka Anna
dc.contributor.authorHoma, Joanna - 128342
dc.contributor.authorGłodzik Wojciech
dc.custom.order1
dc.date.accessioned2024-04-30T07:45:30Z
dc.date.available2024-04-30T07:45:30Z
dc.date.issued2024
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number8
dc.description.versionostateczna wersja wydawcy
dc.description.volume12
dc.identifier.articleide15985
dc.identifier.doi10.14814/phy2.15985
dc.identifier.eissn2051-817X
dc.identifier.urihttps://ruj.uj.edu.pl/handle/item/332324
dc.languageeng
dc.language.containereng
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.typeotwarte czasopismo
dc.subject.encardiovascular disease (CVD)
dc.subject.encytokines
dc.subject.enfatness
dc.subject.enphysical activity
dc.subject.entype 1 diabetes mellitus (T1DM)
dc.subtypeArticle
dc.titleThe effect of physical activity on cytokine levels in adults living with type 1 diabetes : a preliminary study
dc.title.journalPhysiological Reports
dc.typeJournalArticle
dspace.entity.typePublicationen
dc.abstract.en
The aim of this study is to investigate whether physical activity and the level of body fat are factors reducing the level of pro-inflammatory cytokines in people with T1DM. Twenty-five men (27.8 ± 9.4 years old; 178.9 ± 6.9 cm; 80.6 ± 12 kg) and 18 women (28.1 ± 12.5 years old; 162.4 ± 5.5; 63.1 ± 9.9 kg) were divided into four groups based on body fat percentage and level of physical activity (AN—active people with normal body fat; IAN—inactive people with normal body fat; AO—active people with excessive body fat, IAO—inactive people with excessive body fat). The level of cytokines in the blood serum was assessed. The level of IL-8 was higher (measurable) in inactive men, regardless of adiposity degree and in women, only in the inactive group with normal body fat. IL-6 was found only in active men with excessive adiposity. In conclusion, the findings from this study allow to indicate that moderate level of physical activity may contribute to a reduction in the development of systemic low-grade inflammation in patients with T1DM, and thus, may reduce the risk of CVD.
dc.affiliation
Wydział Biologii : Instytut Zoologii i Badań Biomedycznych
dc.contributor.author
Kowal Małgorzata
dc.contributor.author
Woźniacka Renata
dc.contributor.author
Ścisłowska-Czarnecka Anna
dc.contributor.author
Homa, Joanna - 128342
dc.contributor.author
Głodzik Wojciech
dc.custom.order
1
dc.date.accessioned
2024-04-30T07:45:30Z
dc.date.available
2024-04-30T07:45:30Z
dc.date.issued
2024
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.number
8
dc.description.version
ostateczna wersja wydawcy
dc.description.volume
12
dc.identifier.articleid
e15985
dc.identifier.doi
10.14814/phy2.15985
dc.identifier.eissn
2051-817X
dc.identifier.uri
https://ruj.uj.edu.pl/handle/item/332324
dc.language
eng
dc.language.container
eng
dc.rights
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.en
cardiovascular disease (CVD)
dc.subject.en
cytokines
dc.subject.en
fatness
dc.subject.en
physical activity
dc.subject.en
type 1 diabetes mellitus (T1DM)
dc.subtype
Article
dc.title
The effect of physical activity on cytokine levels in adults living with type 1 diabetes : a preliminary study
dc.title.journal
Physiological Reports
dc.type
JournalArticle
dspace.entity.typeen
Publication
Affiliations

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