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Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors
Intracellular redox potential is a highly regulated cellular characteristic and is critically involved in main- taining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reduc- tants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells.
dc.abstract.en | Intracellular redox potential is a highly regulated cellular characteristic and is critically involved in main- taining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reduc- tants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells. | pl |
dc.affiliation | Wydział Chemii : Zakład Fizyki Chemicznej | pl |
dc.affiliation | Pion Rektora : Jagiellońskie Centrum Rozwoju Leków | pl |
dc.contributor.author | Jamieson, Lauren E. | pl |
dc.contributor.author | Jaworska, Aleksandra - 107004 | pl |
dc.contributor.author | Jang, Jiang | pl |
dc.contributor.author | Barańska, Małgorzata - 127224 | pl |
dc.contributor.author | Campbell, Colin J. | pl |
dc.contributor.author | Harrison, David J. | pl |
dc.date.accession | 2019-02-18 | pl |
dc.date.accessioned | 2015-06-22T08:40:51Z | |
dc.date.available | 2015-06-22T08:40:51Z | |
dc.date.issued | 2015 | pl |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.number | 7 | pl |
dc.description.physical | 2330-2335 | pl |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 140 | pl |
dc.identifier.doi | 10.1039/c4an02365j | pl |
dc.identifier.eissn | 1364-5528 | pl |
dc.identifier.issn | 0003-2654 | pl |
dc.identifier.project | ROD UJ / P | pl |
dc.identifier.uri | http://ruj.uj.edu.pl/xmlui/handle/item/9932 | |
dc.identifier.weblink | https://pubs.rsc.org/en/content/articlepdf/2015/an/c4an02365j | pl |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.rights | Udzielam licencji. Uznanie autorstwa 3.0 Polska | * |
dc.rights.licence | CC-BY | |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/legalcode | * |
dc.share.type | inne | |
dc.subtype | Article | pl |
dc.title | Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors | pl |
dc.title.journal | Analyst | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |
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