Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors

2015
journal article
article
62
dc.abstract.enIntracellular redox potential is a highly regulated cellular characteristic and is critically involved in main- taining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reduc- tants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells.pl
dc.affiliationWydział Chemii : Zakład Fizyki Chemicznejpl
dc.affiliationPion Rektora : Jagiellońskie Centrum Rozwoju Lekówpl
dc.contributor.authorJamieson, Lauren E.pl
dc.contributor.authorJaworska, Aleksandra - 107004 pl
dc.contributor.authorJang, Jiangpl
dc.contributor.authorBarańska, Małgorzata - 127224 pl
dc.contributor.authorCampbell, Colin J.pl
dc.contributor.authorHarrison, David J.pl
dc.date.accession2019-02-18pl
dc.date.accessioned2015-06-22T08:40:51Z
dc.date.available2015-06-22T08:40:51Z
dc.date.issued2015pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number7pl
dc.description.physical2330-2335pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume140pl
dc.identifier.doi10.1039/c4an02365jpl
dc.identifier.eissn1364-5528pl
dc.identifier.issn0003-2654pl
dc.identifier.projectROD UJ / Ppl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/9932
dc.identifier.weblinkhttps://pubs.rsc.org/en/content/articlepdf/2015/an/c4an02365jpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 3.0 Polska*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/legalcode*
dc.share.typeinne
dc.subtypeArticlepl
dc.titleSimultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensorspl
dc.title.journalAnalystpl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Intracellular redox potential is a highly regulated cellular characteristic and is critically involved in main- taining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reduc- tants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells.
dc.affiliationpl
Wydział Chemii : Zakład Fizyki Chemicznej
dc.affiliationpl
Pion Rektora : Jagiellońskie Centrum Rozwoju Leków
dc.contributor.authorpl
Jamieson, Lauren E.
dc.contributor.authorpl
Jaworska, Aleksandra - 107004
dc.contributor.authorpl
Jang, Jiang
dc.contributor.authorpl
Barańska, Małgorzata - 127224
dc.contributor.authorpl
Campbell, Colin J.
dc.contributor.authorpl
Harrison, David J.
dc.date.accessionpl
2019-02-18
dc.date.accessioned
2015-06-22T08:40:51Z
dc.date.available
2015-06-22T08:40:51Z
dc.date.issuedpl
2015
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
7
dc.description.physicalpl
2330-2335
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
140
dc.identifier.doipl
10.1039/c4an02365j
dc.identifier.eissnpl
1364-5528
dc.identifier.issnpl
0003-2654
dc.identifier.projectpl
ROD UJ / P
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/9932
dc.identifier.weblinkpl
https://pubs.rsc.org/en/content/articlepdf/2015/an/c4an02365j
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa 3.0 Polska
dc.rights.licence
CC-BY
dc.rights.uri*
http://creativecommons.org/licenses/by/3.0/legalcode
dc.share.type
inne
dc.subtypepl
Article
dc.titlepl
Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors
dc.title.journalpl
Analyst
dc.typepl
JournalArticle
dspace.entity.type
Publication

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