Correlation of volumetric and fractal measurements of brain atrophy with neuropsychological tests in patients with dementive disorders

2008
journal article
article
dc.abstract.enBackground: Brain atrophy is one of the features of the dementive diseases, but also of other neurodegenerative disorders as well as physiological brain aging. The aim of the study was to define the relationship between the brain atrophy measurements and the degree of the severity of dementive process based on the neuropsychological tests (MMSE and Clock Drawing Test). Material/Methods: In 68 patients with diagnosed impairment of cognitive functions due to dementia, neuropsychological tests (MMSE and Clock Drawing Test) and CT studies were performed. On the basis of CT images we evaluated cortical and subcortical atrophy with 3 methods; visual, semiautomatic (volumetric) and automatic method based on fractal geometry calculations; the latter was characterized by very short time of measurements. The correlation between neuropsychological tests and brain atrophy measurements has been assessed using Pearson's correlation test. Results: No statistical correlation was found between the results of neuropsychological tests and measurements of the brain atrophy (both cortical and subcortical) using all three methods mentioned above. Conclusions: Single measurement of the generalized cortical and subcortical atrophy is not correlated with the results of neuropsychological tests. In our opinion, these measurements might be valuable in follow-up of the dementive process to compare progression of the atrophic changes with the changes of the neuropsychological tests results, especially using very quick automatic method, supplemented by local atrophy measurements.pl
dc.contributor.authorCzarnecka, Annapl
dc.contributor.authorSąsiadek, Marek J.pl
dc.contributor.authorHudyma, Elżbietapl
dc.contributor.authorKwaśnicka, Halinapl
dc.contributor.authorParadowski, Mariuszpl
dc.contributor.authorFilarski, Jacekpl
dc.date.accession2019-05-20pl
dc.date.accessioned2019-05-20T06:19:17Z
dc.date.available2019-05-20T06:19:17Z
dc.date.issued2008pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 20pl
dc.description.number4pl
dc.description.physical16-20pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume73pl
dc.identifier.articleid878363pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/75144
dc.identifier.weblinkhttp://archiwum.inforadiologia.pl/download/index/idArt/878363.htmlpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.endementive diseasespl
dc.subject.enbrain atrophypl
dc.subject.encomputed tomographypl
dc.subject.envolumetrypl
dc.subject.enfractalpl
dc.subtypeArticlepl
dc.titleCorrelation of volumetric and fractal measurements of brain atrophy with neuropsychological tests in patients with dementive disorderspl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Background: Brain atrophy is one of the features of the dementive diseases, but also of other neurodegenerative disorders as well as physiological brain aging. The aim of the study was to define the relationship between the brain atrophy measurements and the degree of the severity of dementive process based on the neuropsychological tests (MMSE and Clock Drawing Test). Material/Methods: In 68 patients with diagnosed impairment of cognitive functions due to dementia, neuropsychological tests (MMSE and Clock Drawing Test) and CT studies were performed. On the basis of CT images we evaluated cortical and subcortical atrophy with 3 methods; visual, semiautomatic (volumetric) and automatic method based on fractal geometry calculations; the latter was characterized by very short time of measurements. The correlation between neuropsychological tests and brain atrophy measurements has been assessed using Pearson's correlation test. Results: No statistical correlation was found between the results of neuropsychological tests and measurements of the brain atrophy (both cortical and subcortical) using all three methods mentioned above. Conclusions: Single measurement of the generalized cortical and subcortical atrophy is not correlated with the results of neuropsychological tests. In our opinion, these measurements might be valuable in follow-up of the dementive process to compare progression of the atrophic changes with the changes of the neuropsychological tests results, especially using very quick automatic method, supplemented by local atrophy measurements.
dc.contributor.authorpl
Czarnecka, Anna
dc.contributor.authorpl
Sąsiadek, Marek J.
dc.contributor.authorpl
Hudyma, Elżbieta
dc.contributor.authorpl
Kwaśnicka, Halina
dc.contributor.authorpl
Paradowski, Mariusz
dc.contributor.authorpl
Filarski, Jacek
dc.date.accessionpl
2019-05-20
dc.date.accessioned
2019-05-20T06:19:17Z
dc.date.available
2019-05-20T06:19:17Z
dc.date.issuedpl
2008
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 20
dc.description.numberpl
4
dc.description.physicalpl
16-20
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
73
dc.identifier.articleidpl
878363
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/75144
dc.identifier.weblinkpl
http://archiwum.inforadiologia.pl/download/index/idArt/878363.html
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
dementive diseases
dc.subject.enpl
brain atrophy
dc.subject.enpl
computed tomography
dc.subject.enpl
volumetry
dc.subject.enpl
fractal
dc.subtypepl
Article
dc.titlepl
Correlation of volumetric and fractal measurements of brain atrophy with neuropsychological tests in patients with dementive disorders
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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