Detection of asymptomatic brain involvement in systemic sclerosis

2008
journal article
article
dc.abstract.enBackground: Systemic sclerosis is a chronic connective tissue disease, characterized by vascular changes, accompanied by fibrosis of the skin and internal organs. Neuropsychiatric symptoms are considered rare in these patients. Objectives The aim of the study was to evaluate frequency of morphological brain abnormalities in those patients with systemic sclerosis, who demonstrate no clinical symptoms of central nervous system involvement. Material/Methods: 24 patients with systemic sclerosis, who had no neurological or psychiatric abnormalities were included into the study. In all patients brain magnetic resonance imaging was performed. Fluidattenuated inversion-recovery and fast spin-echo magnetic resonance imaging sequences were used. Results: In 37% (9/24) of these patients brain magnetic resonance images revealed abnormalities. These included: cortical and subcortical atrophy (4/24), single focal lesions (5/24) or diffuse lesions (2/24). In 3 patients simultaneous presence of more then one of these abnormalities was detected. Brain computer tomography revealed abnormalities in 2/24 (8%) of patients. Conclusions: Our results indicate, that the central nervous system may be involved in systemic sclerosis despite lack of neuropsychiatric symptoms. Brain magnetic resonance imaging allows early detection of these abnormalities. We suggest to perform brain magnetic resonance in all patients of systemic sclerosis before introducing treatment.pl
dc.contributor.authorWalecka, Irenapl
dc.contributor.authorSicinska, Justynapl
dc.contributor.authorSzymanska, Elzbietapl
dc.contributor.authorSlowinska, Monikapl
dc.contributor.authorCwikla, Jaroslawpl
dc.contributor.authorOlszewska, Malgorzatapl
dc.contributor.authorPniewski, Jaroslawpl
dc.contributor.authorWalecki, Jerzypl
dc.contributor.authorRudnicka, Lidiapl
dc.date.accession2019-05-20pl
dc.date.accessioned2019-05-20T06:09:41Z
dc.date.available2019-05-20T06:09:41Z
dc.date.issued2008pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 14-15pl
dc.description.number4pl
dc.description.physical12-15pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume73pl
dc.identifier.articleid878362pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/75142
dc.identifier.weblinkhttp://archiwum.inforadiologia.pl/download/index/idArt/878362.htmlpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enbrainpl
dc.subject.enmagnetic resonance imagingpl
dc.subject.ensclerodermapl
dc.subject.ensystemic sclerosispl
dc.subtypeArticlepl
dc.titleDetection of asymptomatic brain involvement in systemic sclerosispl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Background: Systemic sclerosis is a chronic connective tissue disease, characterized by vascular changes, accompanied by fibrosis of the skin and internal organs. Neuropsychiatric symptoms are considered rare in these patients. Objectives The aim of the study was to evaluate frequency of morphological brain abnormalities in those patients with systemic sclerosis, who demonstrate no clinical symptoms of central nervous system involvement. Material/Methods: 24 patients with systemic sclerosis, who had no neurological or psychiatric abnormalities were included into the study. In all patients brain magnetic resonance imaging was performed. Fluidattenuated inversion-recovery and fast spin-echo magnetic resonance imaging sequences were used. Results: In 37% (9/24) of these patients brain magnetic resonance images revealed abnormalities. These included: cortical and subcortical atrophy (4/24), single focal lesions (5/24) or diffuse lesions (2/24). In 3 patients simultaneous presence of more then one of these abnormalities was detected. Brain computer tomography revealed abnormalities in 2/24 (8%) of patients. Conclusions: Our results indicate, that the central nervous system may be involved in systemic sclerosis despite lack of neuropsychiatric symptoms. Brain magnetic resonance imaging allows early detection of these abnormalities. We suggest to perform brain magnetic resonance in all patients of systemic sclerosis before introducing treatment.
dc.contributor.authorpl
Walecka, Irena
dc.contributor.authorpl
Sicinska, Justyna
dc.contributor.authorpl
Szymanska, Elzbieta
dc.contributor.authorpl
Slowinska, Monika
dc.contributor.authorpl
Cwikla, Jaroslaw
dc.contributor.authorpl
Olszewska, Malgorzata
dc.contributor.authorpl
Pniewski, Jaroslaw
dc.contributor.authorpl
Walecki, Jerzy
dc.contributor.authorpl
Rudnicka, Lidia
dc.date.accessionpl
2019-05-20
dc.date.accessioned
2019-05-20T06:09:41Z
dc.date.available
2019-05-20T06:09:41Z
dc.date.issuedpl
2008
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 14-15
dc.description.numberpl
4
dc.description.physicalpl
12-15
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
73
dc.identifier.articleidpl
878362
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/75142
dc.identifier.weblinkpl
http://archiwum.inforadiologia.pl/download/index/idArt/878362.html
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
brain
dc.subject.enpl
magnetic resonance imaging
dc.subject.enpl
scleroderma
dc.subject.enpl
systemic sclerosis
dc.subtypepl
Article
dc.titlepl
Detection of asymptomatic brain involvement in systemic sclerosis
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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