The value of perfusion CT in evaluating locoregional staging in post-radical prostatectomy patients with elevated serum PSA level

2008
journal article
article
dc.abstract.enBackground: The aim of the study was to evaluate the efficiency of perfusion CT (p-CT) in assessing cancer foci in the prostate gland in patients with elevated PSA level who had radical prostatectomy after the p-CT exam. Material/Methods: Prostate p-CT was performed at the Oncology Institute, Cracow, in 2006 in 24 patients aged 49-72 years. The examination was followed by core needle biopsy of the prostate (6-12 cores). PSA levels in the blood ranged from 5.15 to 33.1 ng/ml. The Gleason score estimated after radical prostatectomy ranged from 5 to 8. The parameters BF, BV, PS, and MTT for both prostate lobes at three levels (base, mid-gland, and apex) were measured. Relationships between the presence of pathological foci found in p-CT, serum PSA level, and histopathological findings in the removed prostate gland were analyzed. Results/Conclusions: On the basis of the analyzed material, positive correlation was found between serum PSA level and Gleason score in the post-radical prostatectomy patients. Positive correlation was also found between serum PSA and the presence of pathological lesions detected in p-CT. The higher the level of serum PSA, the higher the probability of detecting a pathological lesion within the prostate gland. No significant correlation between histopathological and p-CT outcome concordance and serum PSA level was noted. However, no correlation between Gleason score and p-CT examination results was found, which suggests that there is no relationship between Gleason score and presence of pathological foci detected in p-CT examination.pl
dc.contributor.authorŁuczyńska, Elżbietapl
dc.contributor.authorAnioł, Joannapl
dc.contributor.authorStelmach, Andrzejpl
dc.contributor.authorJaszczyński, Januszpl
dc.date.accession2019-05-16pl
dc.date.accessioned2019-05-16T12:03:46Z
dc.date.available2019-05-16T12:03:46Z
dc.date.issued2008pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 17pl
dc.description.number2pl
dc.description.physical13-17pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume73pl
dc.identifier.articleid857100pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/74942
dc.identifier.weblinkhttp://archiwum.inforadiologia.pl/download/index/idArt/857100.htmlpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enprostatepl
dc.subject.encarcinomapl
dc.subject.enangiogenesispl
dc.subject.enprostate cancerpl
dc.subject.enperfusionpl
dc.subtypeArticlepl
dc.titleThe value of perfusion CT in evaluating locoregional staging in post-radical prostatectomy patients with elevated serum PSA levelpl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Background: The aim of the study was to evaluate the efficiency of perfusion CT (p-CT) in assessing cancer foci in the prostate gland in patients with elevated PSA level who had radical prostatectomy after the p-CT exam. Material/Methods: Prostate p-CT was performed at the Oncology Institute, Cracow, in 2006 in 24 patients aged 49-72 years. The examination was followed by core needle biopsy of the prostate (6-12 cores). PSA levels in the blood ranged from 5.15 to 33.1 ng/ml. The Gleason score estimated after radical prostatectomy ranged from 5 to 8. The parameters BF, BV, PS, and MTT for both prostate lobes at three levels (base, mid-gland, and apex) were measured. Relationships between the presence of pathological foci found in p-CT, serum PSA level, and histopathological findings in the removed prostate gland were analyzed. Results/Conclusions: On the basis of the analyzed material, positive correlation was found between serum PSA level and Gleason score in the post-radical prostatectomy patients. Positive correlation was also found between serum PSA and the presence of pathological lesions detected in p-CT. The higher the level of serum PSA, the higher the probability of detecting a pathological lesion within the prostate gland. No significant correlation between histopathological and p-CT outcome concordance and serum PSA level was noted. However, no correlation between Gleason score and p-CT examination results was found, which suggests that there is no relationship between Gleason score and presence of pathological foci detected in p-CT examination.
dc.contributor.authorpl
Łuczyńska, Elżbieta
dc.contributor.authorpl
Anioł, Joanna
dc.contributor.authorpl
Stelmach, Andrzej
dc.contributor.authorpl
Jaszczyński, Janusz
dc.date.accessionpl
2019-05-16
dc.date.accessioned
2019-05-16T12:03:46Z
dc.date.available
2019-05-16T12:03:46Z
dc.date.issuedpl
2008
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 17
dc.description.numberpl
2
dc.description.physicalpl
13-17
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
73
dc.identifier.articleidpl
857100
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/74942
dc.identifier.weblinkpl
http://archiwum.inforadiologia.pl/download/index/idArt/857100.html
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
prostate
dc.subject.enpl
carcinoma
dc.subject.enpl
angiogenesis
dc.subject.enpl
prostate cancer
dc.subject.enpl
perfusion
dc.subtypepl
Article
dc.titlepl
The value of perfusion CT in evaluating locoregional staging in post-radical prostatectomy patients with elevated serum PSA level
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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