Evoked cardiac response components in cognitive processing : differential effects of Amyotrophic Lateral Sclerosis

1999
journal article
article
dc.abstract.enWe investigated the mechanism of two evoked cardiac response components associated with different aspects of information processing. Innocuous stimuli presented in an irrelevant condition elicit a simple cardiac deceleration termed ECR1. The same stimuli presented in a relevant condition (such as results from requesting subjects to silently count the stimuli) elicit a complex biphasic response with a large secondary acceleration in heart rate. This difference is attributed to the additional effect of cognitive task performance, resulting in an addition response component, ECR2. This may be realised by subtraction of the two responses. We investigated the mechanisms involved by comparing cardiac response profiles from a neurologically-impaired group with those from a control group. amyotrophic lateral sclerosis (ALS) has been associated with a loss of synaptic connections in the frontal lobe. Twelve ALS clinically non-demented patients were age-matched with twelve neurological patients without pathological changes in the brain. Cardiac response profiles for ECR1 and ECR2 were examined as a function of group. ECR1 did not differ between the groups, but ECR2 was significantly impaired in the ALS patients. The results are discussed in terms of different brain regions associated with these two cardiac response components. ECR1 may be associated with automatic pre attentive stimulus registration involving, in the case of auditory stimuli, the auditory analyser and associated pathways, while ECR2 appears to be a correlate of controlled executive processing, involving the frontal cortex.pl
dc.affiliationWydział Filozoficzny : Instytut Psychologiipl
dc.contributor.authorKaiser, Jan - 128591 pl
dc.contributor.authorWronka, Eligiusz - 132775 pl
dc.contributor.authorBarry, Robertpl
dc.contributor.authorSzczudlik, Andrzejpl
dc.date.accession2015-08-31pl
dc.date.accessioned2015-02-19T17:53:49Z
dc.date.available2015-02-19T17:53:49Z
dc.date.issued1999pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 333-334. Streszcz. ang.pl
dc.description.number4pl
dc.description.physical329-334pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume59pl
dc.identifier.eissn1689-0035pl
dc.identifier.issn0065-1400pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/3223
dc.identifier.weblinkhttp://ane.pl/pdf/5930.pdfpl
dc.languageengpl
dc.language.containerengpl
dc.rights.licenceOTHER
dc.share.typeotwarte czasopismo
dc.subject.enamyotrophic lateral sclerosispl
dc.subject.enevoked cardiac responsepl
dc.subject.encognitive processingpl
dc.subtypeArticlepl
dc.titleEvoked cardiac response components in cognitive processing : differential effects of Amyotrophic Lateral Sclerosispl
dc.title.journalActa Neurobiologiae Experimentalispl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
We investigated the mechanism of two evoked cardiac response components associated with different aspects of information processing. Innocuous stimuli presented in an irrelevant condition elicit a simple cardiac deceleration termed ECR1. The same stimuli presented in a relevant condition (such as results from requesting subjects to silently count the stimuli) elicit a complex biphasic response with a large secondary acceleration in heart rate. This difference is attributed to the additional effect of cognitive task performance, resulting in an addition response component, ECR2. This may be realised by subtraction of the two responses. We investigated the mechanisms involved by comparing cardiac response profiles from a neurologically-impaired group with those from a control group. amyotrophic lateral sclerosis (ALS) has been associated with a loss of synaptic connections in the frontal lobe. Twelve ALS clinically non-demented patients were age-matched with twelve neurological patients without pathological changes in the brain. Cardiac response profiles for ECR1 and ECR2 were examined as a function of group. ECR1 did not differ between the groups, but ECR2 was significantly impaired in the ALS patients. The results are discussed in terms of different brain regions associated with these two cardiac response components. ECR1 may be associated with automatic pre attentive stimulus registration involving, in the case of auditory stimuli, the auditory analyser and associated pathways, while ECR2 appears to be a correlate of controlled executive processing, involving the frontal cortex.
dc.affiliationpl
Wydział Filozoficzny : Instytut Psychologii
dc.contributor.authorpl
Kaiser, Jan - 128591
dc.contributor.authorpl
Wronka, Eligiusz - 132775
dc.contributor.authorpl
Barry, Robert
dc.contributor.authorpl
Szczudlik, Andrzej
dc.date.accessionpl
2015-08-31
dc.date.accessioned
2015-02-19T17:53:49Z
dc.date.available
2015-02-19T17:53:49Z
dc.date.issuedpl
1999
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 333-334. Streszcz. ang.
dc.description.numberpl
4
dc.description.physicalpl
329-334
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
59
dc.identifier.eissnpl
1689-0035
dc.identifier.issnpl
0065-1400
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/3223
dc.identifier.weblinkpl
http://ane.pl/pdf/5930.pdf
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights.licence
OTHER
dc.share.type
otwarte czasopismo
dc.subject.enpl
amyotrophic lateral sclerosis
dc.subject.enpl
evoked cardiac response
dc.subject.enpl
cognitive processing
dc.subtypepl
Article
dc.titlepl
Evoked cardiac response components in cognitive processing : differential effects of Amyotrophic Lateral Sclerosis
dc.title.journalpl
Acta Neurobiologiae Experimentalis
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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