The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy : a cardiac magnetic resonance study

2023
journal article
article
dc.abstract.enPurpose: Hypertrophic cardiomyopathy (HCM) is related with structural and pathologic changes in the left atrium (LA) and left ventricle (LV). The aim of this study was to explore the association between LA mechanics and LV characteristics in patients with HCM using cardiac magnetic resonance feature tracking (CMR-FT). Material and methods: A total of 76 patients with HCM and 26 healthy controls were included in the study. The parameters including the extent of LV late gadolinium enhancement (LGE-%) and the LV early diastolic longitudinal strain rate (edLSR) were assessed for LV. LA conduit, booster, and reservoir functions were assessed by LA fractional volumes and strain analyses using CMR-FT. HCM patients were classified as HCM patients without LGE, with mild LGE-% (0% < LGE-% ≥ 10%), and prominent LGE-% (10% < LGE-%). Results: HCM patients had worse LA functions compared with the controls (p < 0.05). The majority of LA functional indices were more impaired in HCM patients with regard to LGE. LA volumes were higher in HCM patients with prominent LGE-% compared with HCM patients with mild LGE-% (p < 0.05). However, only a minority of LA functional parameters differed between the 2 groups. LA strain parameters showed weak to modest correlations with LV LGE-% and LV edLSR. Conclusions: LV characteristics, to some extent, influence LA mechanics, but they might not be the only factor inducing LA dysfunction in patients with HCM.pl
dc.contributor.authorGuler, Ardapl
dc.contributor.authorTopel, Cagdaspl
dc.contributor.authorSahin, Ahmet Anilpl
dc.contributor.authorAydin, Sinempl
dc.contributor.authorGuler, Ekrempl
dc.contributor.authorSancar, Kadriye Memicpl
dc.contributor.authorCansever, Aysel Turkvatanpl
dc.contributor.authorGuler, Gamze Baburpl
dc.contributor.authorErturk, Mehmetpl
dc.date.accessioned2023-05-05T06:34:37Z
dc.date.available2023-05-05T06:34:37Z
dc.date.issued2023pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e111-e112pl
dc.description.physicale103-e112pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume88pl
dc.identifier.doi10.5114/pjr.2023.125213pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/311098
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.encardiac magnetic resonancepl
dc.subject.enhypertrophic cardiomyopathypl
dc.subject.enleft atriumpl
dc.subject.enlate gadolinium enhancementpl
dc.subtypeArticlepl
dc.titleThe association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy : a cardiac magnetic resonance studypl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Purpose: Hypertrophic cardiomyopathy (HCM) is related with structural and pathologic changes in the left atrium (LA) and left ventricle (LV). The aim of this study was to explore the association between LA mechanics and LV characteristics in patients with HCM using cardiac magnetic resonance feature tracking (CMR-FT). Material and methods: A total of 76 patients with HCM and 26 healthy controls were included in the study. The parameters including the extent of LV late gadolinium enhancement (LGE-%) and the LV early diastolic longitudinal strain rate (edLSR) were assessed for LV. LA conduit, booster, and reservoir functions were assessed by LA fractional volumes and strain analyses using CMR-FT. HCM patients were classified as HCM patients without LGE, with mild LGE-% (0% < LGE-% ≥ 10%), and prominent LGE-% (10% < LGE-%). Results: HCM patients had worse LA functions compared with the controls (p < 0.05). The majority of LA functional indices were more impaired in HCM patients with regard to LGE. LA volumes were higher in HCM patients with prominent LGE-% compared with HCM patients with mild LGE-% (p < 0.05). However, only a minority of LA functional parameters differed between the 2 groups. LA strain parameters showed weak to modest correlations with LV LGE-% and LV edLSR. Conclusions: LV characteristics, to some extent, influence LA mechanics, but they might not be the only factor inducing LA dysfunction in patients with HCM.
dc.contributor.authorpl
Guler, Arda
dc.contributor.authorpl
Topel, Cagdas
dc.contributor.authorpl
Sahin, Ahmet Anil
dc.contributor.authorpl
Aydin, Sinem
dc.contributor.authorpl
Guler, Ekrem
dc.contributor.authorpl
Sancar, Kadriye Memic
dc.contributor.authorpl
Cansever, Aysel Turkvatan
dc.contributor.authorpl
Guler, Gamze Babur
dc.contributor.authorpl
Erturk, Mehmet
dc.date.accessioned
2023-05-05T06:34:37Z
dc.date.available
2023-05-05T06:34:37Z
dc.date.issuedpl
2023
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e111-e112
dc.description.physicalpl
e103-e112
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
88
dc.identifier.doipl
10.5114/pjr.2023.125213
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/311098
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
cardiac magnetic resonance
dc.subject.enpl
hypertrophic cardiomyopathy
dc.subject.enpl
left atrium
dc.subject.enpl
late gadolinium enhancement
dc.subtypepl
Article
dc.titlepl
The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy : a cardiac magnetic resonance study
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.

Views
3
Views per month
Views per city
Ashburn
2
San Jose
1