Novel method for screening of enteric film coatings properties with magnetic resonance imaging

2013
journal article
article
12
dc.abstract.enThe aim of the study is to present the concept of novel method for fast screening of enteric coating compositions properties without the need of preparation of tablets batches for fluid bed coating. Proposed method involves evaluation of enteric coated model tablets in specially designed testing cell with application of MRI technique. The results obtained in the testing cell were compared with results of dissolution studies of mini-tablets coated in fluid bed apparatus. The method could be useful in early stage of formulation development for screening of film coating properties that will shorten and simplify the development works.pl
dc.affiliationWydział Farmaceutyczny : Zakład Technologii Postaci Leku i Biofarmacjipl
dc.cm.id60235
dc.contributor.authorDorożyński, Przemysław - 129211 pl
dc.contributor.authorJamróz, Witold - 129799 pl
dc.contributor.authorNiwiński, Krzysztof - 132986 pl
dc.contributor.authorKurek, Mateusz - 140456 pl
dc.contributor.authorWęglarz, Władysławpl
dc.contributor.authorJachowicz, Renata - 129780 pl
dc.contributor.authorKulinowski, Piotrpl
dc.date.accessioned2015-02-11T13:35:33Z
dc.date.available2015-02-11T13:35:33Z
dc.date.issued2013pl
dc.description.number2pl
dc.description.physical569-571pl
dc.description.volume456pl
dc.identifier.doi10.1016/j.ijpharm.2013.08.004pl
dc.identifier.eissn1873-3476pl
dc.identifier.issn0378-5173pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/3025
dc.languageengpl
dc.language.containerengpl
dc.rightsDodaję tylko opis bibliograficzny*
dc.rights.uri*
dc.subject.enshellacpl
dc.subject.enmini-tabletspl
dc.subject.enenteric coatingpl
dc.subject.endelayed releasepl
dc.subject.enmagnetic resonance imagingpl
dc.subject.enultra-short echo time imagingpl
dc.subject.enMRIpl
dc.subject.enUTEpl
dc.subtypeArticlepl
dc.titleNovel method for screening of enteric film coatings properties with magnetic resonance imagingpl
dc.title.journalInternational Journal of Pharmaceuticspl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
The aim of the study is to present the concept of novel method for fast screening of enteric coating compositions properties without the need of preparation of tablets batches for fluid bed coating. Proposed method involves evaluation of enteric coated model tablets in specially designed testing cell with application of MRI technique. The results obtained in the testing cell were compared with results of dissolution studies of mini-tablets coated in fluid bed apparatus. The method could be useful in early stage of formulation development for screening of film coating properties that will shorten and simplify the development works.
dc.affiliationpl
Wydział Farmaceutyczny : Zakład Technologii Postaci Leku i Biofarmacji
dc.cm.id
60235
dc.contributor.authorpl
Dorożyński, Przemysław - 129211
dc.contributor.authorpl
Jamróz, Witold - 129799
dc.contributor.authorpl
Niwiński, Krzysztof - 132986
dc.contributor.authorpl
Kurek, Mateusz - 140456
dc.contributor.authorpl
Węglarz, Władysław
dc.contributor.authorpl
Jachowicz, Renata - 129780
dc.contributor.authorpl
Kulinowski, Piotr
dc.date.accessioned
2015-02-11T13:35:33Z
dc.date.available
2015-02-11T13:35:33Z
dc.date.issuedpl
2013
dc.description.numberpl
2
dc.description.physicalpl
569-571
dc.description.volumepl
456
dc.identifier.doipl
10.1016/j.ijpharm.2013.08.004
dc.identifier.eissnpl
1873-3476
dc.identifier.issnpl
0378-5173
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/3025
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Dodaję tylko opis bibliograficzny
dc.rights.uri*
dc.subject.enpl
shellac
dc.subject.enpl
mini-tablets
dc.subject.enpl
enteric coating
dc.subject.enpl
delayed release
dc.subject.enpl
magnetic resonance imaging
dc.subject.enpl
ultra-short echo time imaging
dc.subject.enpl
MRI
dc.subject.enpl
UTE
dc.subtypepl
Article
dc.titlepl
Novel method for screening of enteric film coatings properties with magnetic resonance imaging
dc.title.journalpl
International Journal of Pharmaceutics
dc.typepl
JournalArticle
dspace.entity.type
Publication

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