Polymeric/silicagel hybrid molecularly photoimprinted adsorbents for adenosine and its derivatives

2014
journal article
article
10
dc.abstract.enThe adsorbents of adenosine, a potential cancer biomarker present in physiological fluids, urine in particular, were obtained and studied. The adsorbents were fabricated by coating submicron-sized silica gel particles with ultrathin layers of polymers containing thymine moieties. The thymine groups selectively adsorbed compounds containing adenine, a nucleobase complementary to thymine, via the formation of hydrogen bonds. Irradiation of the adsorbents with light selectively absorbed by thymine chromophores in the presence of adenine as a template molecule resulted in the photochemical molecular imprinting of adenine. The non-imprinted adsorbent showed preferential adenosine adsorption from a solution containing a mixture of nucleosides. The adenine-imprinted materials showed considerably higher than non-imprinted adsorbents selectivity of adenosine adsorption versus other nucleosides.pl
dc.affiliationWydział Chemii : Zakład Chemii Fizycznej i Elektrochemiipl
dc.contributor.authorMikulska, Annapl
dc.contributor.authorInoue, Masamichipl
dc.contributor.authorKuroda, Keitapl
dc.contributor.authorGut, Agnieszka - 169976 pl
dc.contributor.authorYusa, Shin-Ichipl
dc.contributor.authorNowakowska, Maria - 131048 pl
dc.contributor.authorSzczubiałka, Krzysztof - 132218 pl
dc.date.accessioned2015-01-15T11:13:07Z
dc.date.available2015-01-15T11:13:07Z
dc.date.issued2014pl
dc.description.additionalNa publikacji autorka Gut Agnieszka podpisana jako Iwanowska Agnieszka.pl
dc.description.admin[AB] Mikulska, Anna 50000141pl
dc.description.physical230-238pl
dc.description.volume59pl
dc.identifier.doi10.1016/j.eurpolymj.2014.07.029pl
dc.identifier.eissn1873-1945pl
dc.identifier.issn0014-3057pl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/2566
dc.languageengpl
dc.language.containerengpl
dc.rights.licencebez licencji
dc.subject.enadenineapl
dc.subject.enadenosinepl
dc.subject.enadsorbentpl
dc.subject.enmolecular imprintingpl
dc.subject.enphotodimerizationpl
dc.subject.enthyminepl
dc.subtypeArticlepl
dc.titlePolymeric/silicagel hybrid molecularly photoimprinted adsorbents for adenosine and its derivativespl
dc.title.journalEuropean Polymer Journalpl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
The adsorbents of adenosine, a potential cancer biomarker present in physiological fluids, urine in particular, were obtained and studied. The adsorbents were fabricated by coating submicron-sized silica gel particles with ultrathin layers of polymers containing thymine moieties. The thymine groups selectively adsorbed compounds containing adenine, a nucleobase complementary to thymine, via the formation of hydrogen bonds. Irradiation of the adsorbents with light selectively absorbed by thymine chromophores in the presence of adenine as a template molecule resulted in the photochemical molecular imprinting of adenine. The non-imprinted adsorbent showed preferential adenosine adsorption from a solution containing a mixture of nucleosides. The adenine-imprinted materials showed considerably higher than non-imprinted adsorbents selectivity of adenosine adsorption versus other nucleosides.
dc.affiliationpl
Wydział Chemii : Zakład Chemii Fizycznej i Elektrochemii
dc.contributor.authorpl
Mikulska, Anna
dc.contributor.authorpl
Inoue, Masamichi
dc.contributor.authorpl
Kuroda, Keita
dc.contributor.authorpl
Gut, Agnieszka - 169976
dc.contributor.authorpl
Yusa, Shin-Ichi
dc.contributor.authorpl
Nowakowska, Maria - 131048
dc.contributor.authorpl
Szczubiałka, Krzysztof - 132218
dc.date.accessioned
2015-01-15T11:13:07Z
dc.date.available
2015-01-15T11:13:07Z
dc.date.issuedpl
2014
dc.description.additionalpl
Na publikacji autorka Gut Agnieszka podpisana jako Iwanowska Agnieszka.
dc.description.adminpl
[AB] Mikulska, Anna 50000141
dc.description.physicalpl
230-238
dc.description.volumepl
59
dc.identifier.doipl
10.1016/j.eurpolymj.2014.07.029
dc.identifier.eissnpl
1873-1945
dc.identifier.issnpl
0014-3057
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/2566
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights.licence
bez licencji
dc.subject.enpl
adeninea
dc.subject.enpl
adenosine
dc.subject.enpl
adsorbent
dc.subject.enpl
molecular imprinting
dc.subject.enpl
photodimerization
dc.subject.enpl
thymine
dc.subtypepl
Article
dc.titlepl
Polymeric/silicagel hybrid molecularly photoimprinted adsorbents for adenosine and its derivatives
dc.title.journalpl
European Polymer Journal
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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