The new method, the old problem : role of contrast-enhanced spectral mammography in the diagnosis of breast cancer among Polish women

2020
journal article
article
cris.lastimport.wos2024-04-09T18:34:00Z
dc.abstract.enPurpose: The aim of the study was to evaluate spectral mammography (CESM) in diagnosing breast cancer, which is based on sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Material and methods: The study included a group of 547 women who underwent spectral mammography and histopathological verification of the lesion, previously seen in mammography and/or ultrasound. In the group of 547 women, 593 focal lesions were diagnosed. All CESM examinations were carried-out with a digital mammography device dedicated to performing dual-energy CESM acquisitions. An intravenous injection of 1.5 ml/kg of body mass of non-ionic contrast agent was performed. Results: The analysis includes 593 breast lesions, in this group cancer was detected in 327 (55.14%) lesions, and in 256 (43.17%) cases benign lesions were confirmed by histopathological examination and at least 12 months of observation. The method shows differentiation of benign and malignant lesions in the breast: sensitivity of 97.86%, specificity of 59.4%, PPV - 74.76%, NPV - 95.76%. Conclusions: Spectral mammography could be an ideal method to detect breast cancer. Thanks to the high NPV (95.76%), it facilitates the exclusion of cancer in situations where pathological contrast enhancement is not observed. The unsatisfactory specificity of the study (59.4%) would not make it safe to avoid a core needle biopsy of lesions that undergo contrast enhancement.pl
dc.contributor.authorSteinhof-Radwańska, Katarzynapl
dc.contributor.authorGrażyńska, Annapl
dc.contributor.authorBarczyk-Gutkowska, Annapl
dc.contributor.authorKajor, Maciejpl
dc.contributor.authorPowązka, Piotrpl
dc.contributor.authorLorek, Andrzejpl
dc.contributor.authorSzlachta-Świątkowska, Ewapl
dc.contributor.authorMorawska, Irminapl
dc.contributor.authorOkas, Karolinapl
dc.contributor.authorLelek, Zuzannapl
dc.contributor.authorBielińska, Magdalenapl
dc.contributor.authorGisterek, Iwonapl
dc.contributor.authorCasañas, Beatapl
dc.contributor.authorPilch-Kowalczyk, Joannapl
dc.date.accessioned2020-10-20T16:04:27Z
dc.date.available2020-10-20T16:04:27Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e386pl
dc.description.physicale381-e386pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume85pl
dc.identifier.doi10.5114/pjr.2020.97941pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/248485
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enbreast cancer diagnosticspl
dc.subject.enspectral mammography (CESM)pl
dc.subject.enmammography (MG)pl
dc.subtypeArticlepl
dc.titleThe new method, the old problem : role of contrast-enhanced spectral mammography in the diagnosis of breast cancer among Polish womenpl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T18:34:00Z
dc.abstract.enpl
Purpose: The aim of the study was to evaluate spectral mammography (CESM) in diagnosing breast cancer, which is based on sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Material and methods: The study included a group of 547 women who underwent spectral mammography and histopathological verification of the lesion, previously seen in mammography and/or ultrasound. In the group of 547 women, 593 focal lesions were diagnosed. All CESM examinations were carried-out with a digital mammography device dedicated to performing dual-energy CESM acquisitions. An intravenous injection of 1.5 ml/kg of body mass of non-ionic contrast agent was performed. Results: The analysis includes 593 breast lesions, in this group cancer was detected in 327 (55.14%) lesions, and in 256 (43.17%) cases benign lesions were confirmed by histopathological examination and at least 12 months of observation. The method shows differentiation of benign and malignant lesions in the breast: sensitivity of 97.86%, specificity of 59.4%, PPV - 74.76%, NPV - 95.76%. Conclusions: Spectral mammography could be an ideal method to detect breast cancer. Thanks to the high NPV (95.76%), it facilitates the exclusion of cancer in situations where pathological contrast enhancement is not observed. The unsatisfactory specificity of the study (59.4%) would not make it safe to avoid a core needle biopsy of lesions that undergo contrast enhancement.
dc.contributor.authorpl
Steinhof-Radwańska, Katarzyna
dc.contributor.authorpl
Grażyńska, Anna
dc.contributor.authorpl
Barczyk-Gutkowska, Anna
dc.contributor.authorpl
Kajor, Maciej
dc.contributor.authorpl
Powązka, Piotr
dc.contributor.authorpl
Lorek, Andrzej
dc.contributor.authorpl
Szlachta-Świątkowska, Ewa
dc.contributor.authorpl
Morawska, Irmina
dc.contributor.authorpl
Okas, Karolina
dc.contributor.authorpl
Lelek, Zuzanna
dc.contributor.authorpl
Bielińska, Magdalena
dc.contributor.authorpl
Gisterek, Iwona
dc.contributor.authorpl
Casañas, Beata
dc.contributor.authorpl
Pilch-Kowalczyk, Joanna
dc.date.accessioned
2020-10-20T16:04:27Z
dc.date.available
2020-10-20T16:04:27Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e386
dc.description.physicalpl
e381-e386
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
85
dc.identifier.doipl
10.5114/pjr.2020.97941
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/248485
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
breast cancer diagnostics
dc.subject.enpl
spectral mammography (CESM)
dc.subject.enpl
mammography (MG)
dc.subtypepl
Article
dc.titlepl
The new method, the old problem : role of contrast-enhanced spectral mammography in the diagnosis of breast cancer among Polish women
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.

Views
37
Views per month
Views per city
New York
4
Ashburn
2
Chandler
2
Dublin
2
Sofia
2
Wroclaw
2
Bensheim
1
Brussels
1
Gdansk
1
Katowice
1
Downloads
steinhof-radwanska_grazynska_barczyk-gutkowska_kajor_powazka_lorek_szlachta-swiatkowska_morawska_okas_lelek_bielinska_gisterek_casanas_pilch-kowalczyk_the_new_method_the_old_problem_2020.pdf
1